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Large language models (LLMs) excel on general tasks yet still hallucinate in high-barrier domains such as pathology. Prior work often relies on domain fine-tuning, which neither expands the knowledge boundary nor enforces evidence-grounded…

计算与语言 · 计算机科学 2025-10-13 Deshui Yu , Yizhi Wang , Saihui Jin , Taojie Zhu , Fanyi Zeng , Wen Qian , Zirui Huang , Jingli Ouyang , Jiameng Li , Zhen Song , Tian Guan , Yonghong He

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Nir Mazor , Tom Hope

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

人工智能 · 计算机科学 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Explaining Deep Learning models is becoming increasingly important in the face of daily emerging multimodal models, particularly in safety-critical domains like medical imaging. However, the lack of detailed investigations into the…

计算机视觉与模式识别 · 计算机科学 2024-03-29 Anees Ur Rehman Hashmi , Dwarikanath Mahapatra , Mohammad Yaqub

Explaining the decision-making processes of Artificial Intelligence (AI) models is crucial for addressing their "black box" nature, particularly in tasks like image classification. Traditional eXplainable AI (XAI) methods typically rely on…

计算机视觉与模式识别 · 计算机科学 2024-11-21 Yifei Zhang , Tianxu Jiang , Bo Pan , Jingyu Wang , Guangji Bai , Liang Zhao

Pathological image segmentation faces numerous challenges, particularly due to ambiguous semantic boundaries and the high cost of pixel-level annotations. Although recent semi-supervised methods based on consistency regularization (e.g.,…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Mingxi Fu , Fanglei Fu , Xitong Ling , Huaitian Yuan , Tian Guan , Yonghong He , Lianghui Zhu

Reliable and interpretable decision-making is essential in medical imaging, where diagnostic outcomes directly influence patient care. Despite advances in deep learning, most medical AI systems operate as opaque black boxes, providing…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Pirzada Suhail , Aditya Anand , Amit Sethi

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Yuzhe Lu , Adam Perer

Recent advances in agentic artificial intelligence, i.e. systems capable of autonomous perception, reasoning, and tool use, offer new opportunities for digital pathology. In this pilot study, we evaluate whether two agentic multimodal AI…

人机交互 · 计算机科学 2026-01-21 Marc Aubreville , Taryn A. Donovan , Christof A. Bertram

Vision language models (VLM) have achieved success in both natural language comprehension and image recognition tasks. However, their use in pathology report generation for whole slide images (WSIs) is still limited due to the huge size of…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Jing Wei Tan , SeungKyu Kim , Eunsu Kim , Sung Hak Lee , Sangjeong Ahn , Won-Ki Jeong

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

机器学习 · 计算机科学 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

Recent advancements in deep neural networks have shown promise in aiding disease diagnosis and medical decision-making. However, ensuring transparent decision-making processes of AI models in compliance with regulations requires a…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Hyeon Bae Kim , Yong Hyun Ahn , Seong Tae Kim

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

计算机视觉与模式识别 · 计算机科学 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial…

图像与视频处理 · 电气工程与系统科学 2024-07-15 Anh Tien Nguyen , Jin Tae Kwak

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

计算机视觉与模式识别 · 计算机科学 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

Deep neural networks have demonstrated superior performance in artificial intelligence applications, but the opaqueness of their inner working mechanism is one major drawback in their application. The prevailing unit-based interpretation is…

计算机视觉与模式识别 · 计算机科学 2024-02-29 Lei Lyu , Chen Pang , Jihua Wang

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Fengyi Zhang , Xujie Zeng , Mohan Liu , Zengyi Wang , Yalong Jiang
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