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The average life expectancy is increasing globally due to advancements in medical technology, preventive health care, and a growing emphasis on gerontological health. Therefore, developing technologies that detect and track aging-associated…

计算工程、金融与科学 · 计算机科学 2022-09-14 Saurav K. Aryal , Howard Prioleau , Legand Burge

Predicting individual cognitive decline in Alzheimer's disease (AD) is difficult due to the heterogeneity of disease progression. Reliable clinical tools require not only high accuracy but also fairness across demographics and robustness to…

人工智能 · 计算机科学 2026-04-27 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Yuzhen Gao , Qianqian Wang , Yongheng Sun , Cui Wang , Yongquan Liang , Mingxia Liu

The paper proposes a novel approach of survival transformers and extreme gradient boosting models in predicting cognitive deterioration in individuals with mild cognitive impairment (MCI) using metabolomics data in the ADNI cohort. By…

机器学习 · 计算机科学 2024-09-25 Henry Musto , Daniel Stamate , Doina Logofatu , Daniel Stahl

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

音频与语音处理 · 电气工程与系统科学 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…

图像与视频处理 · 电气工程与系统科学 2025-03-06 Seunghun Baek , Jaeyoon Sim , Guorong Wu , Won Hwa Kim

The Vision Transformer (ViT) has made significant advancements in computer vision, utilizing self-attention mechanisms to achieve state-of-the-art performance across various tasks, including image classification, object detection, and…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Sehyeong Jo , Gangjae Jang , Haesol Park

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that encompasses a wide variety of symptoms and degrees of impairment, which makes the diagnosis and treatment challenging. Functional magnetic resonance imaging (fMRI) has…

计算机视觉与模式识别 · 计算机科学 2024-09-20 Yinchi Zhou , Peiyu Duan , Yuexi Du , Nicha C. Dvornek

To achieve effective and efficient detection of Alzheimer's disease (AD), many machine learning methods have been introduced into this realm. However, the general case of limited training samples, as well as different feature…

机器学习 · 计算机科学 2013-10-04 Fayao Liu , Luping Zhou , Chunhua Shen , Jianping Yin

Understanding the relationship between cognition and intrinsic brain activity through purely data-driven approaches remains a significant challenge in neuroscience. Resting-state functional magnetic resonance imaging (rs-fMRI) offers a…

机器学习 · 计算机科学 2024-11-01 Yutong Gao , Vince D. Calhoun , Robyn L. Miller

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

图像与视频处理 · 电气工程与系统科学 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Modern Augmented reality applications require performing multiple tasks on each input frame simultaneously. Multi-task learning (MTL) represents an effective approach where multiple tasks share an encoder to extract representative features…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Marina Neseem , Ahmed Agiza , Sherief Reda

Machine learning approaches for Alzheimer's disease (AD) diagnosis face a fundamental challenges. Clinical assessments are expensive and invasive, leaving ground truth labels available for only a fraction of neuroimaging datasets. We…

机器学习 · 计算机科学 2026-03-23 Alireza Moayedikia , Sara Fin

Accurate characterisation of visual attributes such as spiculation, lobulation, and calcification of lung nodules is critical in cancer management. The characterisation of these attributes is often subjective, which may lead to high inter-…

图像与视频处理 · 电气工程与系统科学 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Early and accessible detection of Alzheimer's disease (AD) remains a critical clinical challenge, and cube-copying tasks offer a simple yet informative assessment of visuospatial function. This work proposes a multimodal framework that…

机器学习 · 计算机科学 2025-12-19 Jaeho Yang , Kijung Yoon

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

图像与视频处理 · 电气工程与系统科学 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Accurate multiclass segmentation of the Circle of Willis (CoW) is essential for neurovascular disease management but remains challenging due to complex vascular topology and variable morphology. Existing deep learning methods often suffer…

机器学习 · 计算机科学 2026-05-01 Jialu Liu , Yue Cui , Shan Yu

We propose a novel tensor-on-tensor modeling framework that flexibly models nonlinear voxel-level relationships using Gaussian process (GP) priors, while incorporating the spatial structure of the output tensor through low-rank tensor-based…

统计方法学 · 统计学 2026-04-10 Yajie Liu , Hengrui Luo , Suprateek Kundu

Alzheimer's Disease (AD) is a neurodegenerative condition characterized by diverse progression rates among individuals, with changes in cortical thickness (CTh) closely linked to its progression. Accurately forecasting CTh trajectories can…

图像与视频处理 · 电气工程与系统科学 2024-03-12 Qing Xiao , Siyeop Yoon , Hui Ren , Matthew Tivnan , Lichao Sun , Quanzheng Li , Tianming Liu , Yu Zhang , Xiang Li