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Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

The rapid generation of whole-slide images (WSIs) in dermatopathology necessitates automated methods for efficient processing and accurate classification. This study evaluates the performance of two foundation models, UNI and Virchow2, as…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Riya Gupta , Yiwei Zong , Dennis H. Murphree

Multiple instance learning is an ideal mode of analysis for histopathology data, where vast whole slide images are typically annotated with a single global label. In such cases, a whole slide image is modelled as a collection of tissue…

计算机视觉与模式识别 · 计算机科学 2023-06-29 Leo Fillioux , Joseph Boyd , Maria Vakalopoulou , Paul-Henry Cournède , Stergios Christodoulidis

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

图像与视频处理 · 电气工程与系统科学 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

计算机视觉与模式识别 · 计算机科学 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

图像与视频处理 · 电气工程与系统科学 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

图像与视频处理 · 电气工程与系统科学 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

It is clinically crucial and potentially very beneficial to be able to analyze and model directly the spatial distributions of cells in histopathology whole slide images (WSI). However, most existing WSI datasets lack cell-level…

Automated blood morphology analysis can support hematological diagnostics in low- and middle-income countries (LMICs) but remains sensitive to dataset shifts from staining variability, imaging differences, and rare morphologies. Building…

机器学习 · 计算机科学 2026-01-08 Gabriel Ansah , Eden Ruffell , Delmiro Fernandez-Reyes , Petru Manescu

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

计算机视觉与模式识别 · 计算机科学 2024-09-19 Shaojie Li , Zhaoshuo Diao

Background: Shoulder fractures are often underdiagnosed, especially in emergency and high-volume clinical settings. Studies report up to 10% of such fractures may be missed by radiologists. AI-driven tools offer a scalable way to assist…

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

图像与视频处理 · 电气工程与系统科学 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Reliable facial expression learning (FEL) involves the effective learning of distinctive facial expression characteristics for more reliable, unbiased and accurate predictions in real-life settings. However, current systems struggle with…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Azmine Toushik Wasi , Taki Hasan Rafi , Raima Islam , Karlo Serbetar , Dong Kyu Chae

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics…

计算机视觉与模式识别 · 计算机科学 2024-07-25 Junyu Li , Ye Zhang , Wen Shu , Xiaobing Feng , Yingchun Wang , Pengju Yan , Xiaolin Li , Chulin Sha , Min He

AI-based models for histopathology whole slide image (WSI) analysis are increasingly common, but unsharp or blurred areas within WSI can significantly reduce prediction performance. In this study, we investigated the effect of image blur on…

图像与视频处理 · 电气工程与系统科学 2025-07-21 Yujie Xiang , Bojing Liu , Mattias Rantalainen

Automated analysis of electroencephalography (EEG) has recently undergone a paradigm shift. The introduction of transformer architectures and self-supervised pretraining (SSL) has led to the development of EEG foundation models. These…

神经元与认知 · 定量生物学 2026-02-04 Hannah Portmann , Yosuke Morishima

Proteins and other macromolecules exist not in a single state but as dynamic ensembles of interconverting conformations, which are essential for catalysis, allosteric regulation, and molecular recognition. While AI-based structure…

生物大分子 · 定量生物学 2025-10-22 Stephanie A. Wankowicz , Massimiliano Bonomi

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King
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