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Clinically significant portal hypertension (CSPH) is a severe complication of chronic liver disease associated with cirrhosis, which is diagnosed by the measurement of hepatic venous pressure gradient (HVPG). However, HVPG measurement is…

医学物理 · 物理学 2021-07-13 Kexin Wang , Shuo Wang , Minghua Xiong , Chengyan Wang , He Wang

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

定量方法 · 定量生物学 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

The local beat-to-beat local pulse pressure (PP) and blood pressure waveform of arteries, especially central arteries, are important indicators of the course of cardiovascular diseases (CVDs). Nevertheless, noninvasive measurement of them…

信号处理 · 电气工程与系统科学 2023-05-30 Lirui Xu , Pang Wu , Pan Xia , Fanglin Geng , Peng Wang , Xianxiang Chen , Zhenfeng Li , Lidong Du , Shuping Liu , Li Li , Hongbo Chang , Zhen Fang

Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart…

图像与视频处理 · 电气工程与系统科学 2023-12-25 Michal K. Grzeszczyk , Tadeusz Satlawa , Angela Lungu , Andrew Swift , Andrew Narracott , Rod Hose , Tomasz Trzcinski , Arkadiusz Sitek

Accurate noninvasive estimation of intracranial pressure (ICP) remains a major challenge in critical care. We developed a bespoke machine learning algorithm that integrates system identification and ranking-constrained optimization to…

This paper presents a novel blood pressure (BP) estimation method based on pulse transit time (PTT) and pulse arrival time (PAT) to estimate the systolic BP (SBP) and the diastolic BP (DBP). A data acquisition hardware is designed for…

信号处理 · 电气工程与系统科学 2019-05-08 Amirhossein Esmaili , Mohammad Kachuee , Mahdi Shabany

Precise management of patients with cerebral diseases often requires intracranial pressure (ICP) monitoring, which is highly invasive and requires a specialized ICU setting. The ability to noninvasively estimate ICP is highly compelling as…

医学物理 · 物理学 2019-08-27 Jian-Xun Wang , Xiao Hu , Shawn C. Shadden

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Echocardiographers can detect pulmonary hypertension using Doppler echocardiography; however, accurately assessing its progression often proves challenging. Right heart catheterization (RHC), the gold standard for precise evaluation, is…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Jiewen Yang , Taoran Huang , Shangwei Ding , Xiaowei Xu , Qinhua Zhao , Yong Jiang , Jiarong Guo , Bin Pu , Jiexuan Zheng , Caojin Zhang , Hongwen Fei , Xiaomeng Li

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

机器学习 · 计算机科学 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

This paper presents a novel approach based on pulse transit time (PTT) for the estimation of blood pressure (BP). In order to achieve this goal, a data acquisition hardware is designed for high-resolution sampling of phonocardiogram (PCG)…

信号处理 · 电气工程与系统科学 2019-05-08 Amirhossein Esmaili , Mohammad Kachuee , Mahdi Shabany

Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic…

计算机视觉与模式识别 · 计算机科学 2022-08-09 Christiaan G. A. Viviers , Mark Ramaekers , Peter H. N. de With , Dimitrios Mavroeidis , Joost Nederend , Misha Luyer , Fons van der Sommen

Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…

生物物理 · 物理学 2014-02-27 Suprijadi , Mohamad Rendi , Petrus Subekti , Sparisoma Viridi

Proton Pump Inhibitors (PPIs) are the standard of care for gastric acid disorders but carry significant risks when administered chronically at high doses. Precise long-term control of gastric acidity is challenged by the impracticality of…

系统与控制 · 电气工程与系统科学 2025-07-15 Yutong Li , Ilya Kolmanovsky

Extensive research has been performed on continuous, non-invasive, cuffless blood pressure (BP) measurement using artificial intelligence algorithms. This approach involves extracting certain features from physiological signals like ECG,…

医学物理 · 物理学 2023-04-03 Ali Farki , Reza Baradaran Kazemzadeh , Elham Akhondzadeh Noughabi

Exploiting photoplethysmography signals (PPG) for non-invasive blood pressure (BP) measurement is interesting for various reasons. First, PPG can easily be measured using fingerclip sensors. Second, camera-based approaches allow to derive…

机器学习 · 计算机科学 2021-04-20 Fabian Schrumpf , Patrick Frenzel , Christoph Aust , Georg Osterhoff , Mirco Fuchs

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

Objective: Our study aimed to evaluate and validate PanSegNet, a deep learning (DL) algorithm for pediatric pancreas segmentation on MRI in children with acute pancreatitis (AP), chronic pancreatitis (CP), and healthy controls. Methods:…

Mean aortic pressure (MAP) is a major determinant of perfusion in all organs systems. The ability to forecast MAP would enhance the ability of physicians to estimate prognosis of the patient and assist in early detection of hemodynamic…

机器学习 · 计算机科学 2020-10-20 Eliza Huang , Rui Wang , Uma Chandrasekaran , Rose Yu

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and sustained hypertension is an often silent risk factor, making cuffless continuous blood pressure (BP) monitoring with wearable devices important for…

信号处理 · 电气工程与系统科学 2025-12-02 Yiqiao Chen , Fazheng Xu , Zijian Huang , Juchi He , Zhenghui Feng
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