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This paper puts forth a novel bi-linear modeling framework for data recovery via manifold-learning and sparse-approximation arguments and considers its application to dynamic magnetic-resonance imaging (dMRI). Each temporal-domain MR image…

图像与视频处理 · 电气工程与系统科学 2020-02-28 Gaurav N. Shetty , Konstantinos Slavakis , Abhishek Bose , Ukash Nakarmi , Gesualdo Scutari , Leslie Ying

Musculoskeletal disorders (MSDs) are a leading cause of disability worldwide, requiring advanced diagnostic and therapeutic tools for personalised assessment and treatment. Effective management of MSDs involves the interaction of…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Martina Paccini , Simone Cammarasana , Giuseppe Patanè

This study forms the basis of a digital twin system of the knee joint, using advanced quantitative MRI (qMRI) and machine learning to advance precision health in osteoarthritis (OA) management and knee replacement (KR) prediction. We…

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Digital twins are virtual replicas of physical entities and are poised to transform personalized medicine through the real-time simulation and prediction of human physiology. Translating this paradigm from engineering to biomedicine…

Purpose: Digital twins are virtual interactive models of the real world, exhibiting identical behavior and properties. In surgical applications, computational analysis from digital twins can be used, for example, to enhance situational…

The objective of personalized medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be…

定量方法 · 定量生物学 2024-03-22 Lucas Böttcher , Luis L. Fonseca , Reinhard C. Laubenbacher

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

医学物理 · 物理学 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

Digital Twins technology is revolutionizing decision-making in scientific research by integrating models and simulations with real-time data. Unlike traditional Structural Health Monitoring methods, which rely on computationally intensive…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Mehrdad Shafiei Dizaji

Background: Automated segmentation of spinal MR images plays a vital role both scientifically and clinically. However, accurately delineating posterior spine structures presents challenges. Methods: This retrospective study, approved by the…

Quantifying the uncertainty in predictive models is critical for establishing trust and enabling risk-informed decision making for personalized medicine. In contrast to one-size-fits-all approaches that seek to mitigate risk at the…

计算工程、金融与科学 · 计算机科学 2025-05-15 Graham Pash , Umberto Villa , David A. Hormuth , Thomas E. Yankeelov , Karen Willcox

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data…

定量方法 · 定量生物学 2025-10-21 Luis L. Fonseca , Lucas Böttcher , Borna Mehrad , Reinhard C. Laubenbacher

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

定量方法 · 定量生物学 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

Effective channel estimation in sparse and high-dimensional environments is essential for next-generation wireless systems, particularly in large-scale MIMO deployments. This paper introduces a novel framework that leverages digital twins…

信号处理 · 电气工程与系统科学 2025-04-10 Sadjad Alikhani , Ahmed Alkhateeb

Digital Twin (DT) technology holds immense potential for surgical planning and personalized medicine. However, generating interactive, patient-specific anatomical twins currently relies on computationally heavy Server-Side Rendering (SSR)…

图形学 · 计算机科学 2026-05-20 Oserebameh Augustine Beckley

This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…

图像与视频处理 · 电气工程与系统科学 2024-06-28 Qishi Zhan , Dan Sun , Erdi Gao , Yuhan Ma , Yaxin Liang , Haowei Yang

This research proposal discusses two challenges in the field of medical image analysis: the multi-parametric investigation on microstructural and macrostructural characteristics of the cervical spinal cord and deep learning-based medical…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Maryam Tavakol Elahi

Biomechanical modelling of soft tissue provides a non-data-driven method for constraining medical image registration, such that the estimated spatial transformation is considered biophysically plausible. This has not only been adopted in…

图像与视频处理 · 电气工程与系统科学 2023-02-22 Zhe Min , Zachary M. C. Baum , Shaheer U. Saeed , Mark Emberton , Dean C. Barratt , Zeike A. Taylor , Yipeng Hu

Magnetic resonance imaging (MRI) enables non-invasive, high-resolution analysis of muscle structures. However, automated segmentation remains limited by high computational costs, reliance on large training datasets, and reduced accuracy in…

计算机视觉与模式识别 · 计算机科学 2025-07-14 Mengyuan Liu , Jeongkyu Lee

Vestibular Schwannoma is a benign brain tumour that grows from one of the balance nerves. Patients may be treated by surgery, radiosurgery or with a conservative "wait-and-scan" strategy. Clinicians typically use manually extracted linear…

图像与视频处理 · 电气工程与系统科学 2024-06-05 Navodini Wijethilake , Steve Connor , Anna Oviedova , Rebecca Burger , Tom Vercauteren , Jonathan Shapey
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