相关论文: Driving Accurate Allergen Prediction with Protein …

Studies show that developers' answers to the mobile app users' feedbacks on app stores can increase the apps' star rating. To help app developers generate answers that are related to the users' issues, recent studies develop models to…

Deep learning-based approaches, particularly those leveraging pre-trained language models (PLMs), have shown promise in automated software vulnerability detection. However, existing methods are predominantly limited to specific programming…

The specific region of an antibody responsible for binding to an antigen, known as the paratope, is essential for immune recognition. Accurate identification of this small yet critical region can accelerate the development of therapeutic…

Recent studies have shown the ability of large language models to perform a variety of tasks, including time series forecasting. The flexible nature of these models allows them to be used for many applications. In this paper, we present a…

Typical LLM responses tend to follow a default style, even though users often have distinct preferences regarding tone, verbosity, and formality that they do not explicitly state in their prompts. Evaluating whether personalization methods…

Active Curriculum Language Modeling (ACLM; Hong et al., 2023) is a learner directed approach to training a language model. We proposed the original version of this process in our submission to the BabyLM 2023 task, and now we propose an…

Causal Language Modeling (CLM) and Masked Language Modeling (MLM) are two mainstream learning paradigms based on Transformer networks, specifically the Decoder-only and Encoder-only architectures. The strengths of each paradigm in…

We introduce LLMmap, a first-generation fingerprinting technique targeted at LLM-integrated applications. LLMmap employs an active fingerprinting approach, sending carefully crafted queries to the application and analyzing the responses to…

The task of long-term action anticipation demands solutions that can effectively model temporal dynamics over extended periods while deeply understanding the inherent semantics of actions. Traditional approaches, which primarily rely on…

For protein sequence datasets, unlabeled data has greatly outpaced labeled data due to the high cost of wet-lab characterization. Recent deep-learning approaches to protein prediction have shown that pre-training on unlabeled data can yield…

Modern signal processing (SP) pipelines, whether model-based or data-driven, often constrained by complex and fragmented workflow, rely heavily on expert knowledge and manual engineering, and struggle with adaptability and generalization…

Large Language Models (LLMs) become the start-of-the-art solutions for a variety of natural language tasks and are integrated into real-world applications. However, LLMs can be potentially harmful in manifesting undesirable safety issues…

Predicting protein stability changes induced by single-point mutations has been a persistent challenge over the years, attracting immense interest from numerous researchers. The ability to precisely predict protein thermostability is…

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Large Language Models (LLMs) have made extraordinary progress in the field of Artificial Intelligence and have demonstrated remarkable capabilities across a large variety of tasks and domains. However, as we venture closer to creating…

While large language models (LLMs) are extensively used, there are raising concerns regarding privacy, security, and copyright due to their opaque training data, which brings the problem of detecting pre-training data on the table. Current…

The 21st century is presenting humankind with unprecedented environmental and medical challenges. The ability to design novel proteins tailored for specific purposes could transform our ability to respond timely to these issues. Recent…

The unprecedented advancements in Large Language Models (LLMs) have shown a profound impact on natural language processing but are yet to fully embrace the realm of 3D understanding. This paper introduces PointLLM, a preliminary effort to…

The prediction of protein structures from sequences is an important task for function prediction, drug design, and related biological processes understanding. Recent advances have proved the power of language models (LMs) in processing the…

The ability to accurately model the fitness landscape of protein sequences is critical to a wide range of applications, from quantifying the effects of human variants on disease likelihood, to predicting immune-escape mutations in viruses…