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Predicting the infiltration of Glioblastoma (GBM) from medical MRI scans is crucial for understanding tumor growth dynamics and designing personalized radiotherapy treatment plans.Mathematical models of GBM growth can complement the data in…

机器学习 · 计算机科学 2024-08-19 Ray Zirui Zhang , Ivan Ezhov , Michal Balcerak , Andy Zhu , Benedikt Wiestler , Bjoern Menze , John S. Lowengrub

Glioblastoma (GBM) is the most common aggressive, fast-growing brain tumor, with a grim prognosis. Despite clinical diagnostic advancements, there have not been any substantial improvements to patient prognosis. Histopathological assessment…

计算机视觉与模式识别 · 计算机科学 2025-11-13 Sanyukta Adap , Ujjwal Baid , Spyridon Bakas

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

机器学习 · 计算机科学 2026-02-13 Ankita Paul , Wenyi Wang

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Multimodal Sentiment Analysis (MSA) leverages multiple data modals to analyze human sentiment. Existing MSA models generally employ cutting-edge multimodal fusion and representation learning-based methods to promote MSA capability. However,…

计算与语言 · 计算机科学 2024-12-04 Yijie Jin

Mathematical oncology provides unique and invaluable insights into tumour growth on both the microscopic and macroscopic levels. This review presents state-of-the-art modelling techniques and focuses on their role in understanding…

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

基因组学 · 定量生物学 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Neuroblastoma (NB), a leading cause of childhood cancer mortality, exhibits significant histopathological variability, necessitating precise subtyping for accurate prognosis and treatment. Traditional diagnostic methods rely on subjective…

计算机视觉与模式识别 · 计算机科学 2025-03-20 Huangwei Chen , Yifei Chen , Zhenyu Yan , Mingyang Ding , Chenlei Li , Zhu Zhu , Feiwei Qin

Brain tumors are an abnormal growth of cells in the brain. They can be classified into distinct grades based on their growth. Often grading is performed based on a histological image and is one of the most significant predictors of a…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Omnia Alwazzan , Abbas Khan , Ioannis Patras , Gregory Slabaugh

Accurate, noninvasive glioma characterization is crucial for effective clinical management. Traditional methods, dependent on invasive tissue sampling, often fail to capture the spatial heterogeneity of the tumor. While deep learning has…

图像与视频处理 · 电气工程与系统科学 2025-03-11 Somayeh Farahani , Marjaneh Hejazi , Antonio Di Ieva , Emad Fatemizadeh , Sidong Liu

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Molecular representation learning, a cornerstone for downstream tasks like molecular captioning and molecular property prediction, heavily relies on Graph Neural Networks (GNN). However, GNN suffers from the over-smoothing problem, where…

机器学习 · 计算机科学 2025-08-13 Zihang Shao , Wentao Lei , Lei Wang , Wencai Ye , Li Liu

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

图像与视频处理 · 电气工程与系统科学 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Glioblastoma, a highly aggressive primary brain tumor, is associated with poor patient outcomes. Although magnetic resonance imaging (MRI) plays a critical role in diagnosing, characterizing, and forecasting glioblastoma progression, public…

Accurately assessing tumor removal is paramount in the management of glioblastoma. We developed a pipeline using MRI scans and neural networks to segment tumor subregions and the surgical cavity in postoperative images. Our model excels in…

Graph Neural Networks (GNNs) have been widely employed for feature representation learning in molecular graphs. Therefore, it is crucial to enhance the expressiveness of feature representation to ensure the effectiveness of GNNs. However, a…

机器学习 · 计算机科学 2024-09-16 Chengyu Yao , Hong Huang , Hang Gao , Fengge Wu , Haiming Chen , Junsuo Zhao

Glioblastoma is a highly aggressive and lethal form of brain cancer. Magnetic resonance imaging (MRI) plays a significant role in the diagnosis, treatment planning, and follow-up of glioblastoma patients due to its non-invasive and…

定量方法 · 定量生物学 2023-11-16 Ibrahim Ethem Hamamci