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Single-cell RNA sequencing (scRNA-seq) technology provides high-throughput gene expression data to study the cellular heterogeneity and dynamics of complex organisms. Graph neural networks (GNNs) have been widely used for automatic cell…

机器学习 · 计算机科学 2023-12-19 Rui Yang , Wenrui Dai , Chenglin Li , Junni Zou , Dapeng Wu , Hongkai Xiong

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

机器学习 · 计算机科学 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Graph neural networks (GNNs) are powerful graph-based deep-learning models that have gained significant attention and demonstrated remarkable performance in various domains, including natural language processing, drug discovery, and…

机器学习 · 计算机科学 2023-06-06 Jaykumar Kakkad , Jaspal Jannu , Kartik Sharma , Charu Aggarwal , Sourav Medya

Time series models with recurrent neural networks (RNNs) can have high accuracy but are unfortunately difficult to interpret as a result of feature-interactions, temporal-interactions, and non-linear transformations. Interpretability is…

机器学习 · 计算机科学 2021-09-17 Asif Rahman , Yale Chang , Jonathan Rubin

A large-scale knowledge graph enhances reproducibility in biomedical data discovery by providing a standardized, integrated framework that ensures consistent interpretation across diverse datasets. It improves generalizability by connecting…

统计方法学 · 统计学 2024-10-11 Suqi Liu , Tianxi Cai , Xiaoou Li

Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations…

机器学习 · 计算机科学 2022-02-07 Chengsheng Mao , Liang Yao , Yuan Luo

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

神经元与认知 · 定量生物学 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Tremendous recent literature show that associations between different brain regions, i.e., brain connectivity, provide early symptoms of neurological disorders. Despite significant efforts made for graph neural network (GNN) techniques,…

计算机视觉与模式识别 · 计算机科学 2024-09-27 Xin Ma , Guorong Wu , Seong Jae Hwang , Won Hwa Kim

Interpretable machine learning has emerged as central in leveraging artificial intelligence within high-stakes domains such as healthcare, where understanding the rationale behind model predictions is as critical as achieving high…

机器学习 · 计算机科学 2024-04-30 Christel Sirocchi , Martin Urschler , Bastian Pfeifer

Graph Neural Networks (GNNs) have gained considerable traction for their capability to effectively process topological data, yet their interpretability remains a critical concern. Current interpretation methods are dominated by post-hoc…

机器学习 · 计算机科学 2024-02-08 Jiahua Rao , Jiancong Xie , Hanjing Lin , Shuangjia Zheng , Zhen Wang , Yuedong Yang

While Multi-view Graph Neural Networks (MVGNNs) excel at leveraging diverse modalities for learning object representation, existing methods assume identical local topology structures across modalities that overlook real-world discrepancies.…

机器学习 · 计算机科学 2024-06-05 Peiyu Liang , Hongchang Gao , Xubin He

Classifying research output into context-specific label taxonomies is a challenging and relevant downstream task, given the volume of existing and newly published articles. We propose a method to enhance the performance of article…

机器学习 · 计算机科学 2024-05-29 Khang Ly , Yury Kashnitsky , Savvas Chamezopoulos , Valeria Krzhizhanovskaya

Precise and timely fault diagnosis is a prerequisite for a distribution system to ensure minimum downtime and maintain reliable operation. This necessitates access to a comprehensive procedure that can provide the grid operators with…

人工智能 · 计算机科学 2024-09-11 Dibaloke Chanda , Nasim Yahya Soltani

Multi-view data containing complementary and consensus information can facilitate representation learning by exploiting the intact integration of multi-view features. Because most objects in real world often have underlying connections,…

机器学习 · 计算机科学 2023-08-15 Zhaoliang Chen , Lele Fu , Shunxin Xiao , Shiping Wang , Claudia Plant , Wenzhong Guo

Graph representation learning has been widely studied and demonstrated effectiveness in various graph tasks. Most existing works embed graph data in the Euclidean space, while recent works extend the embedding models to hyperbolic or…

机器学习 · 计算机科学 2023-04-04 Cheng Deng , Fan Xu , Jiaxing Ding , Luoyi Fu , Weinan Zhang , Xinbing Wang

Infectious disease forecasting has been a key focus and proved to be crucial in controlling epidemic. A recent trend is to develop forecast-ing models based on graph neural networks (GNNs). However, existing GNN-based methods suffer from…

机器学习 · 计算机科学 2024-05-28 Mingjie Qiu , Zhiyi Tan , Bing-kun Bao

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

机器学习 · 统计学 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Heterogeneous graph neural networks (HGNNs) have attracted increasing research interest in recent three years. Most existing HGNNs fall into two classes. One class is meta-path-based HGNNs which either require domain knowledge to handcraft…

机器学习 · 计算机科学 2022-09-02 Nan Wu , Chaofan Wang

Recent years have seen a rapid growth of utilizing graph neural networks (GNNs) in the biomedical domain for tackling drug-related problems. However, like any other deep architectures, GNNs are data hungry. While requiring labels in real…

生物物理 · 物理学 2022-05-03 Mengying Sun , Jing Xing , Huijun Wang , Bin Chen , Jiayu Zhou

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

机器学习 · 计算机科学 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal