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The human brain is a complex and highly dynamic system, and our current knowledge of its functional mechanism is still very limited. Fortunately, with functional magnetic resonance imaging (fMRI), we can observe blood oxygen level-dependent…

神经元与认知 · 定量生物学 2024-12-31 Yifei Sun , Mariano Cabezas , Jiah Lee , Chenyu Wang , Wei Zhang , Fernando Calamante , Jinglei Lv

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

定量方法 · 定量生物学 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

Graph neural networks (GNNs) have demonstrated success in learning representations of brain graphs derived from functional magnetic resonance imaging (fMRI) data. However, existing GNN methods assume brain graphs are static over time and…

机器学习 · 计算机科学 2023-07-11 Alexander Campbell , Antonio Giuliano Zippo , Luca Passamonti , Nicola Toschi , Pietro Lio

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

机器学习 · 计算机科学 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

计算机视觉与模式识别 · 计算机科学 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

神经元与认知 · 定量生物学 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

Objective: Endophenotypes such as brain age and fluid intelligence are important biomarkers of disease status. However, brain imaging studies to identify these biomarkers often encounter limited numbers of subjects and high dimensional…

Dynamic functional connectivity (FC) has in recent years become a topic of interest in the neuroimaging community. Several models and methods exist for both functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), and…

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

统计方法学 · 统计学 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

神经元与认知 · 定量生物学 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

Structural magnetic resonance imaging (sMRI) provides accurate estimates of the brain's structural organization and learning invariant brain representations from sMRI is an enduring issue in neuroscience. Previous deep representation…

计算机视觉与模式识别 · 计算机科学 2023-06-21 Ning Jiang , Gongshu Wang , Tianyi Yan

Brain decoding, aiming to identify the brain states using neural activity, is important for cognitive neuroscience and neural engineering. However, existing machine learning methods for fMRI-based brain decoding either suffer from low…

神经元与认知 · 定量生物学 2022-10-13 Ziyuan Ye , Youzhi Qu , Zhichao Liang , Mo Wang , Quanying Liu

Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model…

神经元与认知 · 定量生物学 2022-07-26 Daniel Taylor , Jonathan Shock , Deshendran Moodley , Jonathan Ipser , Matthias Treder

Accurate brain age estimation from structural MRI is a valuable biomarker for studying aging and neurodegeneration. Traditional regression and CNN-based methods face limitations such as manual feature engineering, limited receptive fields,…

计算机视觉与模式识别 · 计算机科学 2025-11-21 Wasif Jalal , Md Nafiu Rahman , Atif Hasan Rahman , M. Sohel Rahman

Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…

神经元与认知 · 定量生物学 2025-04-15 Gang Qu , Ziyu Zhou , Vince D. Calhoun , Aiying Zhang , Yu-Ping Wang

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…

图像与视频处理 · 电气工程与系统科学 2026-04-01 Wanying Qu , Jianxiong Gao , Wei Wang , Yanwei Fu

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…