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Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

HealthBench, a benchmark designed to measure the capabilities of AI systems for health better (Arora et al., 2025), has advanced medical language model evaluation through physician-crafted dialogues and transparent rubrics. However, its…

人工智能 · 计算机科学 2025-08-04 Fred Mutisya , Shikoh Gitau , Nasubo Ongoma , Keith Mbae , Elizabeth Wamicha

Due to the remarkable capabilities and growing impact of large language models (LLMs), they have been deeply integrated into many aspects of society. Thus, ensuring their alignment with human values and intentions has emerged as a critical…

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

Effectively adapting powerful pretrained foundation models to diverse tasks remains a key challenge in AI deployment. Current approaches primarily follow two paradigms:discrete optimization of text prompts through prompt engineering, or…

计算与语言 · 计算机科学 2025-08-06 Xiaoming Hou , Jiquan Zhang , Zibin Lin , DaCheng Tao , Shengli Zhang

Agricultural disease diagnosis challenges VLMs, as conventional fine-tuning requires extensive labels, lacks interpretability, and generalizes poorly. While reasoning improves model robustness, existing methods rely on costly expert…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Wentao Zhang , Mingkun Xu , Qi Zhang , Shangyang Li , Derek F. Wong , Lifei Wang , Yanchao Yang , Lina Lu , Tao Fang

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

计算与语言 · 计算机科学 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

In recent years, Multimodal Large Language Models (MLLM) have achieved notable advancements, demonstrating the feasibility of developing an intelligent biomedical assistant. However, current biomedical MLLMs predominantly focus on…

计算机视觉与模式识别 · 计算机科学 2025-10-09 Xiaoshuang Huang , Lingdong Shen , Jia Liu , Fangxin Shang , Hongxiang Li , Haifeng Huang , Yehui Yang

Aligning Large Language Models (LLMs) with high-stakes medical standards remains a significant challenge, primarily due to the dissonance between coarse-grained preference signals and the complex, multi-dimensional nature of clinical…

人工智能 · 计算机科学 2026-04-10 He Geng , Yangmin Huang , Lixian Lai , Qianyun Du , Hui Chu , Zhiyang He , Jiaxue Hu , Xiaodong Tao

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

计算与语言 · 计算机科学 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text exhibits a fundamentally different uncertainty structure from general text: dense low-confidence…

Medical Vision-Language Models (MedVLMs) excel at perception tasks but struggle with complex clinical reasoning required in real-world scenarios. While reinforcement learning (RL) has been explored to enhance reasoning capabilities,…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Haiqin Zhong , Xiaoling Luo , Wenting Chen , Linlin Shen

Medical AI faces challenges in privacy-preserving collaborative learning while ensuring fairness across heterogeneous healthcare institutions. Current federated learning approaches suffer from static architectures, slow convergence (45-73…

计算机与社会 · 计算机科学 2025-10-24 Jahidul Arafat , Fariha Tasmin , Sanjaya Poudel , Iftekhar Haider

Evaluating large language models (LLMs) in the biomedical domain requires benchmarks that can distinguish reasoning from pattern matching and remain discriminative as model capabilities improve. Existing biomedical question answering (QA)…

Recent Large Multimodal Models have demonstrated remarkable reasoning capabilities, especially in solving complex mathematical problems and realizing accurate spatial perception. Our key insight is that these emerging abilities can…

人工智能 · 计算机科学 2025-05-20 Weiliang Tang , Dong Jing , Jia-Hui Pan , Zhiwu Lu , Yun-Hui Liu , Li Erran Li , Mingyu Ding , Chi-Wing Fu

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

计算与语言 · 计算机科学 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

机器学习 · 计算机科学 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

The integration of large language models (LLMs) into medical practice offers transformative potential, yet their real-world clinical applicability remains constrained by critical alignment issues: (1) a misalignment between static…

人工智能 · 计算机科学 2025-12-05 Yongnan Jin , Xurui Li , Feng Cao , Liucun Gao , Juanjuan Yao