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The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

We investigate the predictability of large language model (LLM) capabilities: given records of past experiments using different model families, numbers of parameters, tasks, and numbers of in-context examples, can we accurately predict LLM…

Large language models (LLMs) have led to a series of breakthroughs in natural language processing (NLP), owing to their excellent understanding and generation abilities. Remarkably, what further sets these models apart is the massive…

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Multimodal Large Language Models (MLLMs) hold great promise for advanced reasoning at the intersection of text and images, yet they have not fully realized this potential. MLLMs typically integrate an LLM, a vision encoder, and a connector…

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Large language models (LLMs) sometimes fail to respond appropriately to deterministic tasks -- such as counting or forming acronyms -- because the implicit prior distribution they have learned over sequences of tokens influences their…

Large language models (LLMs) such as ChatGPT, Gemini, LlaMa, and Claude are trained on massive quantities of text parsed from the internet and have shown a remarkable ability to respond to complex prompts in a manner often indistinguishable…

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Large language models (LLMs) are increasingly deployed in sensitive contexts where fairness and inclusivity are critical. Pronoun usage, especially concerning gender-neutral and neopronouns, remains a key challenge for responsible AI. Prior…

One-size-fits-all large language models (LLMs) are increasingly being used to help people with their writing. However, the style these models are trained to write in may not suit all users or use cases. LLMs would be more useful as writing…

Multimodal Large Language Models (MLLMs) show promise for medical applications, yet progress in dermatology lags due to limited training data, narrow task coverage, and lack of clinically-grounded supervision that mirrors expert diagnostic…

Large Language Models (LLMs) inherit explicit and implicit biases from their training datasets. Identifying and mitigating biases in LLMs is crucial to ensure fair outputs, as they can perpetuate harmful stereotypes and misinformation. This…

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in domains such as visual understanding and mathematical reasoning. However, their application in the medical domain is constrained by two key challenges: (1)…

The upsurge in pre-trained large models started by ChatGPT has swept across the entire deep learning community. Such powerful models demonstrate advanced generative ability and multimodal understanding capability, which quickly set new…

Large vision-language models (LVLMs) have demonstrated exceptional capabilities in understanding visual information with human languages but also exhibit an imbalance in multilingual capabilities. In this work, we delve into the…

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area.…

Multimodal large language models (MLLMs) have shown remarkable performance in vision-language tasks. However, existing MLLMs are primarily trained on generic datasets, limiting their ability to reason on domain-specific visual cues such as…

This review synthesizes the nascent but critical field of developmental interpretability for Large Language Models. We chart the field's evolution from static, post-hoc analysis of trained models to a dynamic investigation of the training…