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Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

光学 · 物理学 2022-01-26 Yi Xue , David Ren , Laura Waller

Spatial resolution in optical microscopy has traditionally been treated as a fixed parameter of the optical system. Here, we present an approach to enhance transverse resolution in beam-scanned optical coherence tomography (OCT) beyond its…

光学 · 物理学 2021-10-22 Nichaluk Leartprapun , Steven G. Adie

Holography has emerged as a vital approach to fully engineer the wavefronts of light since its invention dating back to the last century. However, the typically large pixel size, small field of view and limited space-bandwidth impose…

光学 · 物理学 2019-03-26 Lingling Huang , Shuang Zhang , Thomas Zentgraf

When a laser-cooled atomic sample is optically excited, the envelope of coherent forward scattering can often be decomposed into a few complex Gaussian profiles. The convenience of Gaussian propagation helps addressing key challenges in…

原子物理 · 物理学 2024-12-31 Xing Huang , Yuzhuo Wang , Jian Zhao , Saijun Wu

We present a method for speckle holography that is optimised for crowded fields. Its two key features are an iterativ improvement of the instantaneous Point Spread Functions (PSFs) extracted from each speckle frame and the (optional)…

天体物理仪器与方法 · 物理学 2015-05-30 R. Schoedel , S. Yelda , A. Ghez , J. H. V. Girard , L. Labadie , R. Rebolo , A. Perez-Garrido , M. R. Morris

The waveguide-integrated metasurface introduces a novel photonic chip capable of converting guided modes into free-space light. This enables functions such as off-chip beam focusing, steering, and imaging. The challenge lies in achieving…

光学 · 物理学 2024-07-03 Xianjin Liu , Zhanying Ma , Dasen Zhang , Qiwen Bao , Zhenzhen Liu , Jun-Jun Xiao

Finding, identifying and segmenting suspicious cancer metastasized lymph nodes from 3D multi-modality imaging is a clinical task of paramount importance. In radiotherapy, they are referred to as Lymph Node Gross Tumor Volume (GTVLN).…

图像与视频处理 · 电气工程与系统科学 2020-08-28 Zhuotun Zhu , Dakai Jin , Ke Yan , Tsung-Ying Ho , Xianghua Ye , Dazhou Guo , Chun-Hung Chao , Jing Xiao , Alan Yuille , Le Lu

We demonstrate dark-field x-ray microtomography in a compact, laboratory-based system capable of resolving attenuation, phase, and anisotropic scattering signals with micrometer-scale resolution across centimetre-scale samples. The method…

The GHM multi-level discrete wavelet transform is proposed as preprocessing for image super resolution with convolutional neural networks. Previous works perform analysis with the Haar wavelet only. In this work, 37 single-level wavelets…

图像与视频处理 · 电气工程与系统科学 2022-04-19 Ben Lowe , Hadi Salman , Justin Zhan

We present 3DeepCT, a deep neural network for computed tomography, which performs 3D reconstruction of scattering volumes from multi-view images. Our architecture is dictated by the stationary nature of atmospheric cloud fields. The task of…

图像与视频处理 · 电气工程与系统科学 2020-12-14 Yael Sde-Chen , Yoav Y. Schechner , Vadim Holodovsky , Eshkol Eytan

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording,…

光学 · 物理学 2007-05-23 Sergey A. Alexandrov , P. Meredith , T. J. McIntyre , A. V. Zvyagin

Limited-angle computed tomography (LACT) reconstruction is an inverse problem with severe ill-posedness arising from missing projection angles, and it is difficult to restore high-precision images without sufficient prior knowledge. In…

图像与视频处理 · 电气工程与系统科学 2026-03-06 Hinako Isogai , Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…

光学 · 物理学 2022-10-26 Geng Wang , Stephen A. Boppart , Haohua Tu

Mapping blood microflows of the whole brain is crucial for early diagnosis of cerebral diseases. Ultrasound localization microscopy (ULM) was recently applied to map and quantify blood microflows in 2D in the brain of adult patients down to…

医学物理 · 物理学 2023-04-12 Hugues Favre , Mathieu Pernot , Mickael Tanter , Clément Papadacci

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To…

图像与视频处理 · 电气工程与系统科学 2021-06-07 Figen S. Oktem , Oğuzhan Fatih Kar , Can Deniz Bezek , Farzad Kamalabadi

Multifocus microscopy enables recording of entire volumes in a single camera exposure. In dense samples, multifocus microscopy is severely hampered by background haze. Here, we introduce a scalable multifocus method that incorporates…

The 3D structure of light scattering from dark-field illuminated live 3T3 cells marked with 40 nm gold nanomarkers is explored. For this purpose, we use a high resolution holographic microscope combining the off-axis heterodyne geometry and…

Three-dimensional (3D) imaging of thin, extended specimens at nanometer resolution is critical for applications in biology, materials science, advanced synthesis, and manufacturing. One route to 3D imaging is tomography, which requires a…

仪器与探测器 · 物理学 2023-10-23 Deepan Balakrishnan , See Wee Chee , Zhaslan Baraissov , Michel Bosman , Utkur Mirsaidov , N. Duane Loh

A wide range of biomedical applications requires enhancement, detection, quantification and modelling of curvilinear structures in 2D and 3D images. Curvilinear structure enhancement is a crucial step for further analysis, but many of the…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Shuaa S. Alharbi , Cigdem Sazak , Carl J. Nelson , Boguslaw Obara

As intensities of MRI volumes are inconsistent across institutes, it is essential to extract universal features of multi-modal MRIs to precisely segment brain tumors. In this concept, we propose a volumetric vision transformer that follows…

图像与视频处理 · 电气工程与系统科学 2022-09-19 Himashi Peiris , Munawar Hayat , Zhaolin Chen , Gary Egan , Mehrtash Harandi
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