相关论文: AutoPCR: Automated Phenotype Concept Recognition b…

Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Fine-grained entity typing (FET), which assigns entities in text with context-sensitive, fine-grained semantic types, is a basic but important task for knowledge extraction from unstructured text. FET has been studied extensively in natural…

Objective: Clinical deep phenotyping and phenotype annotation play a critical role in both the diagnosis of patients with rare disorders as well as in building computationally-tractable knowledge in the rare disorders field. These processes…

The remarkable success of pretrained language models has motivated the study of what kinds of knowledge these models learn during pretraining. Reformulating tasks as fill-in-the-blanks problems (e.g., cloze tests) is a natural approach for…

Fine-tuned pre-trained language models (PLMs) have achieved awesome performance on almost all NLP tasks. By using additional prompts to fine-tune PLMs, we can further stimulate the rich knowledge distributed in PLMs to better serve…

Ontology learning is a critical task in industry, dealing with identifying and extracting concepts captured in text data such that these concepts can be used in different tasks, e.g. information retrieval. Ontology learning is non-trivial…

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Linking (aligning) biomedical concepts across diverse data sources enables various integrative analyses, but it is challenging due to the discrepancies in concept naming conventions. Various strategies have been developed to overcome this…

Continuous prompts have become widely adopted for augmenting performance across a wide range of natural language tasks. However, the underlying mechanism of this enhancement remains obscure. Previous studies rely on individual words for…

As one of the fundamental tasks in text analysis, phrase mining aims at extracting quality phrases from a text corpus. Phrase mining is important in various tasks such as information extraction/retrieval, taxonomy construction, and topic…

Concepts benefit natural language understanding but are far from complete in existing knowledge graphs (KGs). Recently, pre-trained language models (PLMs) have been widely used in text-based concept extraction (CE). However, PLMs tend to…

Classification of pathological images is the basis for automatic cancer diagnosis. Despite that deep learning methods have achieved remarkable performance, they heavily rely on labeled data, demanding extensive human annotation efforts. In…

In the expansion of biomedical dataset, the same category may be labeled with different terms, thus being tedious and onerous to curate these terms. Therefore, automatically mapping synonymous terms onto the ontologies is desirable, which…

Recent progress in large-scale CLIP-like vision-language models(VLMs) has greatly advanced medical image analysis. However, most existing medical VLMs still rely on coarse image-text contrastive objectives and fail to capture the systematic…

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Prompt-based fine-tuning has become an essential method for eliciting information encoded in pre-trained language models for a variety of tasks, including text classification. For multi-class classification tasks, prompt-based fine-tuning…

We hypothesize that large language models (LLMs) based on the transformer architecture can enable automated detection of clinical phenotype terms, including terms not documented in the HPO. In this study, we developed two types of models:…

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Large Language Models (LLMs) are gaining significant popularity in recent years for specialized tasks using prompts due to their low computational cost. Standard methods like prefix tuning utilize special, modifiable tokens that lack…