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Image-based patient-specific simulation of left ventricular (LV) mechanics is valuable for understanding cardiac function and supporting clinical intervention planning, but conventional finite-element analysis (FEA) is computationally…

机器学习 · 计算机科学 2026-02-09 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

Background: Cardiac MRI derived biventricular mass and function parameters, such as end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), stroke volume (SV), and ventricular mass (VM) are clinically well…

计算机视觉与模式识别 · 计算机科学 2017-06-15 Hinrich B Winther , Christian Hundt , Bertil Schmidt , Christoph Czerner , Johann Bauersachs , Frank Wacker , Jens Vogel-Claussen

In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

计算机视觉与模式识别 · 计算机科学 2018-11-22 Ehab Abdelmaguid , Jolene Huang , Sanjay Kenchareddy , Disha Singla , Laura Wilke , Mai H. Nguyen , Ilkay Altintas

Segmentation of cardiac structures is one of the fundamental steps to estimate volumetric indices of the heart. This step is still performed semi-automatically in clinical routine, and is thus prone to inter- and intra-observer variability.…

Automated construction of surface geometries of cardiac structures from volumetric medical images is important for a number of clinical applications. While deep-learning-based approaches have demonstrated promising reconstruction precision,…

图像与视频处理 · 电气工程与系统科学 2021-09-15 Fanwei Kong , Nathan Wilson , Shawn C. Shadden

Segmentation of the Left ventricle (LV) is a crucial step for quantitative measurements such as area, volume, and ejection fraction. However, the automatic LV segmentation in 2D echocardiographic images is a challenging task due to…

图像与视频处理 · 电气工程与系统科学 2019-12-24 Shakiba Moradi , Mostafa Ghelich-Oghli , Azin Alizadehasl , Isaac Shiri , Niki Oveisi , Mehrdad Oveisi , Majid Maleki , Jan Dhooge

Finite element analysis (FEA) forms the cornerstone of modeling cardiac biomechanics but is computationally expensive, limiting its clinical application for digital twin creation, which often requires tens to hundreds of simulations to…

医学物理 · 物理学 2025-04-29 Lei Shi , Yurui Chen , Vijay Vedula

In the field of heart disease classification, two primary obstacles arise. Firstly, existing Electrocardiogram (ECG) datasets consistently demonstrate imbalances and biases across various modalities. Secondly, these time-series data consist…

机器学习 · 计算机科学 2024-07-31 Thao Hoang , Linh Nguyen , Khoi Do , Duong Nguyen , Viet Dung Nguyen

The prediction of heart surface potentials using measurements from the body's surface is known as the inverse problem of electrocardiography. It is an ill-posed problem due to the multiple factors that affect the heart signal as it…

医学物理 · 物理学 2019-02-06 Joe Horvath , Lu Shien , Tommy Peng , Avinash Malik , Mark Trew , Laura Bear

Electrocardiograms (ECGs) provide non-invasive measurements of heart activity and are established tools for detecting cardiac arrhythmias. Although supervised machine learning has emerged as a promising approach for automated heartbeat…

机器学习 · 计算机科学 2026-04-27 Amir Reza Vazifeh , Jason W. Fleischer

Healthcare is one of the most important aspects of human life. Heart disease is known to be one of the deadliest diseases which is hampering the lives of many people around the world. Heart disease must be detected early so the loss of…

机器学习 · 计算机科学 2024-09-04 Shadab Hussain , Santosh Kumar Nanda , Susmith Barigidad , Shadab Akhtar , Md Suaib , Niranjan K. Ray

Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Gilles Van De Vyver , Sarina Thomas , Guy Ben-Yosef , Sindre Hellum Olaisen , Håvard Dalen , Lasse Løvstakken , Erik Smistad

Cardiac left ventricle (LV) quantification is among the most clinically important tasks for identification and diagnosis of cardiac diseases, yet still a challenge due to the high variability of cardiac structure and the complexity of…

计算机视觉与模式识别 · 计算机科学 2017-06-15 Wufeng Xue , Andrea Lum , Ashley Mercado , Mark Landis , James Warringto , Shuo Li

Left ventricular ejection fraction (LVEF) is a key indicator of cardiac function and plays a central role in the diagnosis and management of cardiovascular disease. Echocardiography, as a readily accessible and non-invasive imaging…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Shravan Saranyan , Pramit Saha

Electrocardiogram (ECG) detection and delineation are key steps for numerous tasks in clinical practice, as ECG is the most performed non-invasive test for assessing cardiac condition. State-of-the-art algorithms employ digital signal…

机器学习 · 计算机科学 2020-05-12 Guillermo Jimenez-Perez , Alejandro Alcaine , Oscar Camara

An electrocardiogram (ECG) monitors the electrical activity generated by the heart and is used to detect fatal cardiovascular diseases (CVDs). Conventionally, to capture the precise electrical activity, clinical experts use multiple-lead…

医学物理 · 物理学 2023-07-24 Ekansh Chauhan , Swathi Guptha , Likith Reddy , Bapi Raju

Coronary artery disease, caused by the narrowing of coronary vessels due to atherosclerosis, is the leading cause of death worldwide. The diagnostic gold standard, fractional flow reserve (FFR), measures the trans-stenotic pressure ratio…

Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in…

Solving inverse problems in cardiac electrophysiology consists in the recovery of physiological parameters from surface electrocardiogram (ECG) measurements, a task which is often computationally unfeasible due to the severe ill-posedness…

MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…

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