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Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Large language models (LLMs) have demonstrated remarkable capabilities in various scientific domains, from natural language processing to complex problem-solving tasks. Their ability to understand and generate human-like text has opened up…

计算与语言 · 计算机科学 2024-11-05 Guangzhi Xiong , Eric Xie , Amir Hassan Shariatmadari , Sikun Guo , Stefan Bekiranov , Aidong Zhang

Conventional Retrieval Augmented Generation (RAG) approaches are common in text-based applications. However, they struggle with structured, interconnected datasets like knowledge graphs, where understanding underlying relationships is…

信息检索 · 计算机科学 2025-07-15 Savini Kashmira , Jayanaka L. Dantanarayana , Krisztián Flautner , Lingjia Tang , Jason Mars

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

计算与语言 · 计算机科学 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Advancements in natural language processing have revolutionized the way we can interact with digital information systems, such as databases, making them more accessible. However, challenges persist, especially when accuracy is critical, as…

计算与语言 · 计算机科学 2025-11-12 Larissa Pusch , Tim O. F. Conrad

Hypothesis generation is a fundamental step in scientific discovery, yet it is increasingly challenged by information overload and disciplinary fragmentation. Recent advances in Large Language Models (LLMs) have sparked growing interest in…

While Large Language Models (LLMs) demonstrate exceptional performance in a multitude of Natural Language Processing (NLP) tasks, they encounter challenges in practical applications, including issues with hallucinations, inadequate…

计算与语言 · 计算机科学 2024-06-13 Yihao Li , Ru Zhang , Jianyi Liu

Recent advancements in Large Language Models (LLMs) have showcased their proficiency in answering natural language queries. However, their effectiveness is hindered by limited domain-specific knowledge, raising concerns about the…

Large Language Models (LLMs) face significant limitations when applied to large-scale graphs, struggling with context constraints and inflexible reasoning. We present GraphChain, a framework that enables LLMs to analyze complex graphs…

人工智能 · 计算机科学 2025-11-11 Chunyu Wei , Wenji Hu , Xingjia Hao , Xin Wang , Yifan Yang , Yueguo Chen , Yang Tian , Yunhai Wang

Knowledge graphs (KGs) are vital for knowledge-intensive tasks and have shown promise in reducing hallucinations in large language models (LLMs). However, constructing high-quality KGs remains difficult, requiring accurate information…

计算与语言 · 计算机科学 2025-10-14 Ruirui Chen , Weifeng Jiang , Chengwei Qin , Bo Xiong , Fiona Liausvia , Dongkyu Choi , Boon Kiat Quek

Current knowledge graph (KG) construction methods are confirmatory, focusing on recovering known relationships rather than identifying novel or context-dependent nodes. This paper proposes a phenotype-driven and evidence-governed framework…

人工智能 · 计算机科学 2026-04-21 Adela Bâra , Simona-Vasilica Oprea

We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

信息检索 · 计算机科学 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

Large Language Models (LLMs) excel at language understanding but remain limited in knowledge-intensive domains due to hallucinations, outdated information, and limited explainability. Text-based retrieval-augmented generation (RAG) helps…

计算与语言 · 计算机科学 2026-02-09 Larissa Pusch , Alexandre Courtiol , Tim Conrad

Large Language Models (LLMs) have revolutionized Natural Language Processing (NLP) based applications including automated text generation, question answering, chatbots, and others. However, they face a significant challenge: hallucinations,…

计算与语言 · 计算机科学 2024-11-22 Ernests Lavrinovics , Russa Biswas , Johannes Bjerva , Katja Hose

Large language models (LLMs) excel in generating fluent utterances but can lack reliable grounding in verified information. At the same time, knowledge-graph-based fact-checkers deliver precise and interpretable evidence, yet suffer from…

计算与语言 · 计算机科学 2025-11-06 Shaghayegh Kolli , Richard Rosenbaum , Timo Cavelius , Lasse Strothe , Andrii Lata , Jana Diesner

Large language model (LLM) has achieved outstanding performance on various downstream tasks with its powerful natural language understanding and zero-shot capability, but LLM still suffers from knowledge limitation. Especially in scenarios…

计算与语言 · 计算机科学 2024-08-07 Tiezheng Guo , Qingwen Yang , Chen Wang , Yanyi Liu , Pan Li , Jiawei Tang , Dapeng Li , Yingyou Wen

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, including multi-step reasoning such as mathematical proving. However, existing approaches often lack an explicit and…

计算与语言 · 计算机科学 2026-05-19 Yutong Li , Yitian Zhou , Xudong Wang , GuoChen , Caiyan Qin

Large language models (LLMs) have achieved remarkable performance in natural language understanding and generation tasks. However, they often suffer from limitations such as difficulty in incorporating new knowledge, generating…

人工智能 · 计算机科学 2024-03-05 Yilin Wen , Zifeng Wang , Jimeng Sun

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KNOWNET a visualization system…

人机交互 · 计算机科学 2024-09-27 Youfu Yan , Yu Hou , Yongkang Xiao , Rui Zhang , Qianwen Wang

In recent years, Natural Language Processing (NLP) has played a significant role in various Artificial Intelligence (AI) applications such as chatbots, text generation, and language translation. The emergence of large language models (LLMs)…

计算与语言 · 计算机科学 2024-07-10 Amanda Kau , Xuzeng He , Aishwarya Nambissan , Aland Astudillo , Hui Yin , Amir Aryani
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