相关论文: Learning Patient-Specific Spatial Biomarker Dynami…
Alzheimer's disease (AD) is an irreversible and progressive brain disease that can be stopped or slowed down with medical treatment. Language changes serve as a sign that a patient's cognitive functions have been impacted, potentially…
Normative modeling is an emerging and promising approach to effectively study disorder heterogeneity in individual participants. In this study, we propose a novel normative modeling method by combining conditional variational autoencoder…
Understanding the relationship between cognition and intrinsic brain activity through purely data-driven approaches remains a significant challenge in neuroscience. Resting-state functional magnetic resonance imaging (rs-fMRI) offers a…
Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative disorders in humans. Because a significant percentage of patients have clinical and pathological features of both diseases, it has been…
Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with increasing prevalence among the aging population, necessitating early and accurate diagnosis for effective disease management. In this study, we present a novel…
Alzheimer's disease is characterised by the spreading of misfolded proteins and progressive structural changes in the brain. Despite significant clinical research, understanding how microscopic protein dynamics translate into macroscopic…
Objectives: The objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease (AD) prediction and to highlight the potential of AI techniques in improving early AD…
Alzheimer's disease (AD) is a complex neurodegenerative condition that manifests at multiple levels and involves a spectrum of abnormalities ranging from the cellular to cognitive. Here, we investigate the impact of AD-related tau-pathology…
Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…
Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…
This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…
We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…
Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…
Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…
Subjective cognitive decline (SCD) is a preclinical stage of Alzheimer's disease (AD) which occurs even before mild cognitive impairment (MCI). Progressive SCD will convert to MCI with the potential of further evolving to AD. Therefore,…
Alzheimer disease (AD) is a neurodegenerative disease that lacks specific treatment options. Natural drugs have displayed neuroprotective effects; however, their high-throughput discovery is challenging because of the expense of…
Structural magnetic resonance imaging (MRI) studies have shown that Alzheimer's Disease (AD) induces both localised and widespread neural degenerative changes throughout the brain. However, the absence of segmentation that highlights brain…
Deep learning, a cutting-edge machine learning approach, outperforms traditional machine learning in identifying intricate structures in complex high-dimensional data, particularly in the domain of healthcare. This study focuses on…
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease; yet its currently available treatments are limited to stopping disease progression. Moreover, effectiveness of these treatments is not guaranteed due to the…