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Articular cartilage showcases distinctive mechanical behaviour, attributable to its biphasic composition and hierarchical organization. Proteoglycans, essential constituents of the extracellular matrix, contribute to tissue swelling,…

医学物理 · 物理学 2025-10-24 S. Fantoni , M. Berni , R. Fognani , G. Fraterrigo , P. Cardarelli , F. Baruffaldi , M. Baleani

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

Material decomposition in X-ray imaging uses the energy-dependence of attenuation to virtually decompose an object into specific constituent materials. X-ray phase contrast imaging is a developing technique that can enhance image contrast…

To guide surgical and medical treatment X-ray images have been used by physicians in every modern healthcare organization and hospitals. Doctor's evaluation process and disease identification in the area of skeletal system can be performed…

计算机视觉与模式识别 · 计算机科学 2019-05-22 Rafsanjany Kushol , Md. Nishat Raihan , Md Sirajus Salekin , A. B. M. Ashikur Rahman

Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

图像与视频处理 · 电气工程与系统科学 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

Recent innovations in x-ray technology (namely phase-based and energy-resolved imaging) offer unprecedented opportunities for material discrimination, however they are often used in isolation or in limited combinations. Here we show that…

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

仪器与探测器 · 物理学 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

医学物理 · 物理学 2025-08-19 Giavanna Jadick , Patrick La Rivière

We previously demonstrated near-field speckle scanning based x-ray imaging to be an easy-to-implement phase sensing method capable of providing both high sensitivity and high resolution. Yet, this performance combination could only be…

医学物理 · 物理学 2017-06-21 Sebastien Berujon , Eric Ziegler

X-ray imaging is the most widely used medical imaging modality. However, in the common practice, inconsistency in the initial presentation of X-ray images is a common complaint by radiologists. Different patient positions, patient habitus…

图像与视频处理 · 电气工程与系统科学 2025-01-22 Hongxu Yang , Najib Akram Aboobacker , Xiaomeng Dong , German Gonzalez , Lehel Ferenczi , Gopal Avinash

Fabrication of X-ray gratings has surged in the last two decades thanks to their vast employment in X-ray Phase Contrast Imaging, an imaging technique able to boost X-ray sensitivity to detect otherwise invisible details. These high aspect…

Phase-contrast and dark-field imaging are relatively new X-ray imaging modalities that provide additional information to conventional attenuation-based imaging. However, this new information comes at the price of a more complex acquisition…

Imaging of microvasculature is primarily performed with X-ray contrast agents, owing to the wide availability of absorption-contrast laboratory source microCT compared to phase contrast capable devices. Standard commercial contrast agents…

组织与器官 · 定量生物学 2023-01-18 Willy Kuo , Ngoc An Le , Bernhard Spingler , Georg Schulz , Bert Müller , Vartan Kurtcuoglu

X-ray imaging, traditionally relying on attenuation contrast, struggles to differentiate materials with similar attenuation coefficients like soft tissues. X-ray phase contrast imaging (XPCI) and dark-field (DF) imaging provide enhanced…

医学物理 · 物理学 2025-06-05 Jingcheng Yuan , Mini Das

X-ray grating interferometry is an excellent technique for X-ray phase contrast imaging and X-ray wavefront sensing with applications in materials science, biology and medical diagnosis. Among other requirements, the method depends on the…

X-ray microtomography is a versatile tool allowing the measurement of the 3D structure of optically thick samples. As a non-destructive technique, it is readily adapted to 4D imaging, where a sample can be monitored over time, and…

仪器与探测器 · 物理学 2025-12-17 Harry Allan , Tom Partridge , Joseph Jacob , Marco Endrizzi

X-ray phase contrast imaging offers a way to visualize the internal structures of an object without the need to deposit any radiation, and thereby alleviate the main concern in x-ray diagnostic imaging procedures today. Grating-based…

X-ray radiography is the most readily available imaging modality and has a broad range of applications that spans from diagnosis to intra-operative guidance in cardiac, orthopedics, and trauma procedures. Proper interpretation of the hidden…

计算机视觉与模式识别 · 计算机科学 2019-04-19 Shadi Albarqouni , Javad Fotouhi , Nassir Navab

X-ray phase-contrast imaging has the potential to improve image contrast with lower dose by probing an object's refractive properties as well as its absorptive properties. To reconstruct a phase-contrast image from a raw dataset, a phase…

医学物理 · 物理学 2025-08-19 Giavanna Jadick , Patrick La Rivière

Purpose: Grating-based X-ray phase-contrast imaging is a promising modality increasing the soft tissue contrast in medical imaging. In this work, the signature of lung tissue in X-ray grating-based physe-contrast imaging is investigated.…

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