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Accurate prediction of antibody-antigen (Ab-Ag) binding affinity is essential for therapeutic design and vaccine development, yet the performance of current models is limited by noisy experimental labels, heterogeneous assay conditions, and…

With the growing use of language models (LMs) in clinical environments, there is an immediate need to evaluate the accuracy and safety of LM-generated medical text. Currently, such evaluation relies solely on manual physician review.…

AI agents could accelerate scientific discovery by automating hypothesis formation, experiment design, coding, execution, and analysis, yet existing benchmarks probe narrow skills in simplified settings. To address this gap, we introduce…

Large Language Models have demonstrated strong performance on many established reasoning benchmarks. However, these benchmarks primarily evaluate structured skills like quantitative problem-solving, leaving a gap in assessing flexible,…

计算与语言 · 计算机科学 2025-10-30 Deepon Halder , Alan Saji , Thanmay Jayakumar , Ratish Puduppully , Anoop Kunchukuttan , Raj Dabre

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

Autonomous AI research agents aim to accelerate scientific discovery by automating the research pipeline, from hypothesis generation to peer review. However, existing benchmarks rarely test a fundamental bottleneck: whether Large Language…

机器学习 · 计算机科学 2026-05-29 Sy-Tuyen Ho , Minghui Liu , Huy Nghiem , Furong Huang

Convex analysis is a modern branch of mathematics with many applications. As Large Language Models (LLMs) start to automate research-level math and sciences, it is important for LLMs to demonstrate the ability to understand and reason with…

人工智能 · 计算机科学 2026-02-05 Yepeng Liu , Yu Huang , Yu-Xiang Wang , Yingbin Liang , Yuheng Bu

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

计算与语言 · 计算机科学 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

计算与语言 · 计算机科学 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

Logical reasoning is fundamental for humans yet presents a substantial challenge in the domain of Artificial Intelligence. Initially, researchers used Knowledge Representation and Reasoning (KR) systems that did not scale and required…

计算与语言 · 计算机科学 2024-04-02 Man Luo , Shrinidhi Kumbhar , Ming shen , Mihir Parmar , Neeraj Varshney , Pratyay Banerjee , Somak Aditya , Chitta Baral

Argumentation skills are an essential toolkit for large language models (LLMs). These skills are crucial in various use cases, including self-reflection, debating collaboratively for diverse answers, and countering hate speech. In this…

计算与语言 · 计算机科学 2026-04-21 Yamen Ajjour , Carlotta Quensel , Nedim Lipka , Henning Wachsmuth

We introduce SATBench, a benchmark for evaluating the logical reasoning capabilities of large language models (LLMs) through logical puzzles derived from Boolean satisfiability (SAT) problems. Unlike prior work that focuses on inference…

人工智能 · 计算机科学 2025-09-23 Anjiang Wei , Yuheng Wu , Yingjia Wan , Tarun Suresh , Huanmi Tan , Zhanke Zhou , Sanmi Koyejo , Ke Wang , Alex Aiken

Large language models (LLMs) have emerged as a potential solution to automate the complex processes involved in writing literature reviews, such as literature collection, organization, and summarization. However, it is yet unclear how good…

计算与语言 · 计算机科学 2025-08-22 Xuemei Tang , Xufeng Duan , Zhenguang G. Cai

The goal of achieving Artificial General Intelligence (AGI) is to imitate humans and surpass them. Models such as OpenAI's o1, o3, and DeepSeek's R1 have demonstrated that large language models (LLMs) with human-like reasoning capabilities…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Yansheng Qiu , Li Xiao , Zhaopan Xu , Pengfei Zhou , Zheng Wang , Kaipeng Zhang

Automated Essay Scoring (AES) has been explored for decades with the goal to support teachers by reducing grading workload and mitigating subjective biases. While early systems relied on handcrafted features and statistical models, recent…

计算与语言 · 计算机科学 2026-03-09 Jonas Kubesch , Lena Huber , Clemens Havas

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Recent developments in large language models (LLMs) have shown promise in enhancing the capabilities of natural language processing (NLP). Despite these successes, there remains a dearth of research dedicated to the NLP problem-solving…

计算与语言 · 计算机科学 2023-10-20 Linxin Song , Jieyu Zhang , Lechao Cheng , Pengyuan Zhou , Tianyi Zhou , Irene Li

While large language models (LLMs) excel at many domain-specific tasks, their ability to deeply comprehend and reason about full-length academic papers remains underexplored. Existing benchmarks often fall short of capturing such depth,…

人工智能 · 计算机科学 2026-01-08 Xinbang Dai , Huikang Hu , Yongrui Chen , Jiaqi Li , Rihui Jin , Yuyang Zhang , Xiaoguang Li , Lifeng Shang , Guilin Qi

Agents based on Large Language Models (LLMs) have shown promise for performing sophisticated software engineering tasks autonomously. In addition, there has been progress towards developing agents that can perform parts of the research…

计算与语言 · 计算机科学 2026-04-23 Nicholas Edwards , Yukyung Lee , Yujun Audrey Mao , Yulu Qin , Sebastian Schuster , Najoung Kim

Retrieval-Augmented Generation (RAG) is a framework in which a Generator, such as a Large Language Model (LLM), produces answers by retrieving documents from an external collection using a Retriever. In practice, Generators must integrate…

计算与语言 · 计算机科学 2026-04-30 Koki Itai , Shunichi Hasegawa , Yuta Yamamoto , Gouki Minegishi , Masaki Otsuki