中文
相关论文

相关论文: Protenix-Mini: Efficient Structure Predictor via C…

200 篇论文

Distilled diffusion models accelerate image generation by reducing the number of denoising steps, but often suffer from degraded image quality. To mitigate this trade-off, test-time optimization methods improve quality, yet their iterative…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Haewon Jeon , Si-Hyeon Lee

In recent developments, the Mamba architecture, known for its selective state space approach, has shown potential in the efficient modeling of long sequences. However, its application in image generation remains underexplored. Traditional…

计算机视觉与模式识别 · 计算机科学 2024-05-28 Shentong Mo , Yapeng Tian

We study the scaling properties of latent diffusion models (LDMs) with an emphasis on their sampling efficiency. While improved network architecture and inference algorithms have shown to effectively boost sampling efficiency of diffusion…

计算机视觉与模式识别 · 计算机科学 2024-12-11 Kangfu Mei , Zhengzhong Tu , Mauricio Delbracio , Hossein Talebi , Vishal M. Patel , Peyman Milanfar

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

定量方法 · 定量生物学 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

We introduce Efficient Motion Diffusion Model (EMDM) for fast and high-quality human motion generation. Current state-of-the-art generative diffusion models have produced impressive results but struggle to achieve fast generation without…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Wenyang Zhou , Zhiyang Dou , Zeyu Cao , Zhouyingcheng Liao , Jingbo Wang , Wenjia Wang , Yuan Liu , Taku Komura , Wenping Wang , Lingjie Liu

Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…

生物大分子 · 定量生物学 2025-03-25 Zhongyue Zhang , Runze Ma , Yanjie Huang , Shuangjia Zheng

Proteins perform their biological functions through three-dimensional structures encoded by amino acid sequences, and ligand-binding protein co-design requires models that generate sequence-structure compatible proteins under explicit…

生物大分子 · 定量生物学 2026-05-28 Chen Wei , Fanding Xu , Minghao Sun , Zhiyuan Liu , Lin Wang , Tianrui Jia , Yihang Zhou , Yang Zhang

Large pre-trained DNA language models such as DNABERT-2, Nucleotide Transformer, and HyenaDNA have demonstrated strong performance on various genomic benchmarks. However, most applications rely on expensive fine-tuning, which works best…

基因组学 · 定量生物学 2025-08-08 Nirjhor Datta , Swakkhar Shatabda , M Sohel Rahman

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

图像与视频处理 · 电气工程与系统科学 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Learning meaningful protein representation is important for a variety of biological downstream tasks such as structure-based drug design. Having witnessed the success of protein sequence pretraining, pretraining for structural data which is…

机器学习 · 计算机科学 2023-02-23 Yufei Huang , Lirong Wu , Haitao Lin , Jiangbin Zheng , Ge Wang , Stan Z. Li

Recently segment anything model (SAM) has shown powerful segmentation capability and has drawn great attention in computer vision fields. Massive following works have developed various applications based on the pre-trained SAM and achieved…

计算机视觉与模式识别 · 计算机科学 2025-01-09 Han Shu , Wenshuo Li , Yehui Tang , Yiman Zhang , Yihao Chen , Houqiang Li , Yunhe Wang , Xinghao Chen

This paper discusses predictive inference and feature selection for generalized linear models with scarce but high-dimensional data. We argue that in many cases one can benefit from a decision theoretically justified two-stage approach:…

机器学习 · 统计学 2020-11-09 Juho Piironen , Markus Paasiniemi , Aki Vehtari

Behavioural differences across organisms, whether healthy or pathological, are closely tied to the structure of their neural circuits. Yet, the fine-scale synaptic changes that give rise to these variations remain poorly understood, in part…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Samia Mohinta , Daniel Franco-Barranco , Shi Yan Lee , Albert Cardona

Although deep learning-based personalized recommendation systems provide qualified recommendations, they strain data center resources. The main bottleneck is the embedding layer, which is highly memory-intensive due to its sparse, irregular…

硬件体系结构 · 计算机科学 2025-11-26 Youngsuk Kim , Junghwan Lim , Hyuk-Jae Lee , Chae Eun Rhee

Many high-performance networks were not designed with lightweight application scenarios in mind from the outset, which has greatly restricted their scope of application. This paper takes ConvNeXt as the research object and significantly…

计算机视觉与模式识别 · 计算机科学 2025-08-29 Fang Wang , Huitao Li , Wenhan Chao , Zheng Zhuo , Yiran Ji , Chang Peng , Yupeng Sun

Monocular depth estimation (MDE) aims to infer per-pixel depth from a single RGB image. While diffusion models have advanced MDE with impressive generalization, they often exhibit limitations in accurately reconstructing far-range regions.…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Mingxia Zhan , Li Zhang , Yingjie Wang , Xiaomeng Chu , Beibei Wang , Yanyong Zhang

Diffusion magnetic resonance imaging (dMRI) is an important tool in characterizing tissue microstructure based on biophysical models, which are complex and highly non-linear. Resolving microstructures with optimization techniques is prone…

信号处理 · 电气工程与系统科学 2022-05-16 Tianshu Zheng , Cong Sun , Weihao Zheng , Wen Shi , Haotian Li , Yi Sun , Yi Zhang , Guangbin Wang , Chuyang Ye , Dan Wu

While deep neural networks (NN) significantly advance image compressed sensing (CS) by improving reconstruction quality, the necessity of training current CS NNs from scratch constrains their effectiveness and hampers rapid deployment.…

计算机视觉与模式识别 · 计算机科学 2025-02-04 Bin Chen , Zhenyu Zhang , Weiqi Li , Chen Zhao , Jiwen Yu , Shijie Zhao , Jie Chen , Jian Zhang

The diffusion model has demonstrated promising results in image generation, recently becoming mainstream and representing a notable advancement for many generative modeling tasks. Prior applications of the diffusion model for both fast…

仪器与探测器 · 物理学 2025-06-18 Cheng Jiang , Sitian Qian , Huilin Qu

Trajectory data is crucial for various applications but often suffers from incompleteness due to device limitations and diverse collection scenarios. Existing imputation methods rely on sparse trajectory or travel information, such as…

机器学习 · 计算机科学 2025-05-30 Tianci Bu , Le Zhou , Wenchuan Yang , Jianhong Mou , Kang Yang , Suoyi Tan , Feng Yao , Jingyuan Wang , Xin Lu