相关论文: TextOmics-Guided Diffusion for Hit-like Molecular …

When reliable target structures are unavailable at scale or phenotypes arise from dysregulated pathways, transcriptomic perturbations provide a system-level functional readout for drug action. In this work, we formalize…

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

We propose a Distributional Approach for addressing Controlled Text Generation from pre-trained Language Models (LMs). This approach permits to specify, in a single formal framework, both "pointwise" and "distributional" constraints over…

In Text-to-Image (T2I) generation, the complexity of entities and their intricate interactions pose a significant challenge for T2I method based on diffusion model: how to effectively control entity and their interactions to produce…

Diffusion models have demonstrated remarkable performance in generating unimodal data across various tasks, including image, video, and text generation. On the contrary, the joint generation of multimodal data through diffusion models is…

Recently, the strong latent Diffusion Probabilistic Model (DPM) has been applied to high-quality Text-to-Image (T2I) generation (e.g., Stable Diffusion), by injecting the encoded target text prompt into the gradually denoised diffusion…

Novel diffusion models can synthesize photo-realistic images with integrated high-quality text. Surprisingly, we demonstrate through attention activation patching that only less than $1$% of diffusion models' parameters, all contained in…

Multi-Source Diffusion Models (MSDM) allow for compositional musical generation tasks: generating a set of coherent sources, creating accompaniments, and performing source separation. Despite their versatility, they require estimating the…

Three-dimensional molecular generators based on diffusion models can now reach near-crystallographic accuracy, yet they remain fragmented across tasks. SMILES-only inputs, two-stage pretrain-finetune pipelines, and one-task-one-model…

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details…

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Generative models have shown great promise in generating 3D geometric systems, which is a fundamental problem in many natural science domains such as molecule and protein design. However, existing approaches only operate on static…

Text-to-image diffusion models can synthesize high-quality images, but they have various limitations. Here we highlight a common failure mode of these models, namely, generating uncommon concepts and structured concepts like hand palms. We…

Text-driven human motion generation is a multimodal task that synthesizes human motion sequences conditioned on natural language. It requires the model to satisfy textual descriptions under varying conditional inputs, while generating…

Text-to-image (TTI) generative models can be used to generate photorealistic images from a given text-string input. These models offer great potential to mitigate challenges to the uptake of machine learning in the earth sciences. However,…

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Diffusion based Text-To-Music (TTM) models generate music corresponding to text descriptions. Typically UNet based diffusion models condition on text embeddings generated from a pre-trained large language model or from a cross-modality…

Text-to-image generative models can generate high-quality humans, but realism is lost when generating hands. Common artifacts include irregular hand poses, shapes, incorrect numbers of fingers, and physically implausible finger…

Text-to-image (T2I) generation has greatly enhanced creative expression, yet achieving preference-aligned generation in a real-time and training-free manner remains challenging. Previous methods often rely on static, pre-collected…

Image tokenizers form the foundation of modern text-to-image generative models but are notoriously difficult to train. Furthermore, most existing text-to-image models rely on large-scale, high-quality private datasets, making them…