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Many real-world graphs (networks) are heterogeneous with different types of nodes and edges. Heterogeneous graph embedding, aiming at learning the low-dimensional node representations of a heterogeneous graph, is vital for various…

社会与信息网络 · 计算机科学 2021-12-15 Wentao Xu , Yingce Xia , Weiqing Liu , Jiang Bian , Jian Yin , Tie-Yan Liu

Graph Neural Networks (GNNs) are de facto node classification models in graph structured data. However, during testing-time, these algorithms assume no data shift, i.e., $\Pr_\text{train}(X,Y) = \Pr_\text{test}(X,Y)$. Domain adaption…

机器学习 · 计算机科学 2022-03-31 Qi Zhu , Chao Zhang , Chanyoung Park , Carl Yang , Jiawei Han

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

基因组学 · 定量生物学 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular processes by enabling gene expression analysis at the individual cell level. Clustering allows for the identification of cell types and the further…

机器学习 · 计算机科学 2025-06-03 Ziwen Wang

Capturing semantic consistency among nodes is crucial for effective graph representation learning. Existing approaches typically rely on $k$-nearest neighbors ($k$NN) or other node-level full search algorithms (FSA) to mine semantic…

人工智能 · 计算机科学 2026-05-06 Genhao Tian , Taihua Xu , Shuyin Xia , Qinghua Zhang , Jie Yang , Jianjun Chen

Single-cell RNA sequencing (scRNA-seq) has emerged as a transformative technology, offering unparalleled insights into the intricate landscape of cellular diversity and gene expression dynamics. The analysis of scRNA-seq data poses…

分子网络 · 定量生物学 2023-12-19 Hongsong Feng , Sean Cottrell , Yuta Hozumi , Guo-Wei Wei

Benefiting from the intrinsic supervision information exploitation capability, contrastive learning has achieved promising performance in the field of deep graph clustering recently. However, we observe that two drawbacks of the positive…

机器学习 · 计算机科学 2023-01-04 Xihong Yang , Yue Liu , Sihang Zhou , Siwei Wang , Wenxuan Tu , Qun Zheng , Xinwang Liu , Liming Fang , En Zhu

We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data. scTree corrects for batch effects while simultaneously learning a…

机器学习 · 计算机科学 2024-07-11 Moritz Vandenhirtz , Florian Barkmann , Laura Manduchi , Julia E. Vogt , Valentina Boeva

Since its selection as the method of the year in 2013, single-cell technologies have become mature enough to provide answers to complex research questions. With the growth of single-cell profiling technologies, there has also been a…

Graph condensation, which reduces the size of a large-scale graph by synthesizing a small-scale condensed graph as its substitution, has immediate benefits for various graph learning tasks. However, existing graph condensation methods rely…

机器学习 · 计算机科学 2023-10-24 Xin Zheng , Miao Zhang , Chunyang Chen , Quoc Viet Hung Nguyen , Xingquan Zhu , Shirui Pan

Self-supervised heterogeneous graph learning (SHGL) has shown promising potential in diverse scenarios. However, while existing SHGL methods share a similar essential with clustering approaches, they encounter two significant limitations:…

人工智能 · 计算机科学 2024-12-03 Yujie Mo , Zhihe Lu , Runpeng Yu , Xiaofeng Zhu , Xinchao Wang

Single-cell RNA sequencing (scRNA-seq) determines RNA expression at single-cell resolution. It provides a powerful tool for studying immunity, regulation, and other life activities of cells. However, due to the limitations of the sequencing…

基因组学 · 定量生物学 2024-02-16 Linfeng Jiang , Yuan Zhu

Graph classification is essential for understanding complex biological systems, where molecular structures and interactions are naturally represented as graphs. Traditional graph neural networks (GNNs) perform well on static tasks but…

机器学习 · 计算机科学 2025-10-29 Ding Zhang , Jane Downer , Can Chen , Ren Wang

Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies and experimental protocols have led to the generation of vast amounts of genomic data that populates several online databases and repositories. Here, we…

基因组学 · 定量生物学 2024-04-17 Mahnoor N. Gondal , Saad Ur Rehman Shah , Arul M. Chinnaiyan , Marcin Cieslik

How can we find meaningful clusters in a graph robustly against noise edges? Graph clustering (i.e., dividing nodes into groups of similar ones) is a fundamental problem in graph analysis with applications in various fields. Recent studies…

机器学习 · 计算机科学 2023-11-09 Hyeonsoo Jo , Fanchen Bu , Kijung Shin

Graph clustering is an essential aspect of network analysis that involves grouping nodes into separate clusters. Recent developments in deep learning have resulted in graph clustering, which has proven effective in many applications.…

机器学习 · 计算机科学 2026-01-05 Yang Xiang , Li Fan , Tulika Saha , Xiaoying Pang , Yushan Pan , Haiyang Zhang , Chengtao Ji

Graph clustering, which aims to divide nodes in the graph into several distinct clusters, is a fundamental yet challenging task. Benefiting from the powerful representation capability of deep learning, deep graph clustering methods have…

机器学习 · 计算机科学 2023-09-13 Yue Liu , Jun Xia , Sihang Zhou , Xihong Yang , Ke Liang , Chenchen Fan , Yan Zhuang , Stan Z. Li , Xinwang Liu , Kunlun He

Graph Neural Networks have emerged as a useful tool to learn on the data by applying additional constraints based on the graph structure. These graphs are often created with assumed intrinsic relations between the entities. In recent years,…

机器学习 · 统计学 2021-05-18 Sunil Kumar Maurya , Xin Liu , Tsuyoshi Murata

In this study, we present the Graph Sub-Graph Network (GSN), a novel hybrid image classification model merging the strengths of Convolutional Neural Networks (CNNs) for feature extraction and Graph Neural Networks (GNNs) for structural…

计算机视觉与模式识别 · 计算机科学 2024-10-01 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

机器学习 · 计算机科学 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu