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Convolutional Neural Networks have become a cornerstone of medical image analysis due to their proficiency in learning hierarchical spatial features. However, this focus on a single domain is inefficient at capturing global, holistic…
Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…
Missing data is a common problem in machine learning and in retrospective imaging research it is often encountered in the form of missing imaging modalities. We propose to take into account missing modalities in the design and training of…
For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…
Deep learning models, such as the fully convolutional network (FCN), have been widely used in 3D biomedical segmentation and achieved state-of-the-art performance. Multiple modalities are often used for disease diagnosis and quantification.…
Accurate medical imaging segmentation is critical for precise and effective medical interventions. However, despite the success of convolutional neural networks (CNNs) in medical image segmentation, they still face challenges in handling…
Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…
Foundation models pre-trained on large-scale natural image datasets offer a powerful paradigm for medical image segmentation. However, effectively transferring their learned representations for precise clinical applications remains a…
Incomplete multi-modal medical image segmentation faces critical challenges from modality imbalance, including imbalanced modality missing rates and heterogeneous modality contributions. Due to their reliance on idealized assumptions of…
Biomedical image segmentation is a critical task in medical diagnosis and treatment planning, enabling precise delineation of anatomical structures and pathological regions. Despite significant advancements, challenges persist due to the…
Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this…
Solving variational image segmentation problems with hidden physics is often expensive and requires different algorithms and manually tunes model parameter. The deep learning methods based on the U-Net structure have obtained outstanding…
Spinal surgery planning necessitates automatic segmentation of vertebrae in cone-beam computed tomography (CBCT), an intraoperative imaging modality that is widely used in intervention. However, CBCT images are of low-quality and…
Existing few-shot medical image segmentation (FSMIS) models fail to address a practical issue in medical imaging: the domain shift caused by different imaging techniques, which limits the applicability to current FSMIS tasks. To overcome…
Due to the computational complexity of 3D medical image segmentation, training with downsampled images is a common remedy for out-of-memory errors in deep learning. Nevertheless, as standard spatial convolution is sensitive to variations in…
Cross modal image syntheses is gaining significant interests for its ability to estimate target images of a different modality from a given set of source images,like estimating MR to MR, MR to CT, CT to PET etc, without the need for an…
Accurate segmentation of organs and tumors in CT and MRI scans is essential for diagnosis, treatment planning, and disease monitoring. While deep learning has advanced automated segmentation, most models remain task-specific, lacking…
Volumetric medical image segmentation is pivotal in enhancing disease diagnosis, treatment planning, and advancing medical research. While existing volumetric foundation models for medical image segmentation, such as SAM-Med3D and SegVol,…
Deep learning has achieved tremendous success in computer vision, while medical image segmentation (MIS) remains a challenge, due to the scarcity of data annotations. Meta-learning techniques for few-shot segmentation (Meta-FSS) have been…
Segmentation of 3D medical images is a critical task for accurate diagnosis and treatment planning. Convolutional neural networks (CNNs) have dominated the field, achieving significant success in 3D medical image segmentation. However, CNNs…