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Nanophotonic devices excel at confining light into intense hot spots of the electromagnetic near fields, creating unprecedented opportunities for light-matter coupling and surface-enhanced sensing. Recently, all-dielectric metasurfaces with…

The biomedical imaging world is notorious for working with small amounts of data, frustrating state-of-the-art efforts in the computer vision and deep learning worlds. With large datasets, it is easier to make progress we have seen from the…

计算机视觉与模式识别 · 计算机科学 2022-12-08 Manuel Serna-Aguilera , Khoa Luu , Nathaniel Harris , Min Zou

Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…

We present a new methodology for efficient and high-quality patterning of biological reagents for surface-based biological assays. The method relies on hydrodynamically confined nanoliter volumes of reagents to interact with the substrate…

生物大分子 · 定量生物学 2016-04-27 J. Autebert , J. F. Cors , David P. Taylor , G. V. Kaigala

Nutrient limitation is one of the most common triggers of antibiotic tolerance and persistence. Here, we present two microfluidic setups to study how spatial and temporal variation in nutrient availability lead to increased survival of…

定量方法 · 定量生物学 2020-10-29 Stefany Moreno-Gámez , Alma Dal Co , Simon van Vliet , Martin Ackermann

Biofilms in porous media critically influence hydraulic properties in environmental and engineered systems. However, a mechanistic understanding of how microbial life controls permeability remains elusive. By combining microfluidics,…

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

软凝聚态物质 · 物理学 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

Droplet motion on surfaces influences phenomena as diverse as microfluidic liquid handling, printing technology and micro-organism migration. Typically, droplet motion is achieved by inducing energy gradients on a substrate or flow on the…

软凝聚态物质 · 物理学 2020-10-02 Robert Malinowski , Ivan P. Parkin , Giorgio Volpe

Plants and insects use slender conical structures to transport and collect small droplets, which are propelled along the conical structures due to capillary action. These droplets can deposit a fluid film during their motion, but despite…

流体动力学 · 物理学 2021-01-27 Tak Shing Chan , Carmen L. Lee , Christian Pedersen , Kari Dalnoki-Veress , Andreas Carlson

For visual estimation of optical flow, a crucial function for many vision tasks, unsupervised learning, using the supervision of view synthesis has emerged as a promising alternative to supervised methods, since ground-truth flow is not…

计算机视觉与模式识别 · 计算机科学 2023-04-17 Zitang Sun , Shin'ya Nishida , Zhengbo Luo

Microorganismal motility is often characterised by complex responses to environmental physico-chemical stimuli. Although the biological basis of these responses is often not well understood, their exploitation already promises novel avenues…

生物物理 · 物理学 2019-11-26 Jorge Arrieta , Marco Polin , Ramón Saleta-Piersanti , Idan Tuval

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often characterized by intricate, non-even surfaces. However, the impact of surface irregularities on the population dynamics of biofilms remains elusive…

种群与进化 · 定量生物学 2023-08-31 Witold Postek , Klaudia Staskiewicz , Elin Lilja , Bartlomiej Waclaw

Biolasers made of biological materials have attracted a great of research attention due to their biocompatibility and biodegradability, which have the potential for biosensors and biointegration. However, the current fabrication method of…

Microbiomes are a vital part of the human body, engaging in tasks like food digestion and immune defense. Their structure and function must be understood in order to promote host health and facilitate swift recovery during disease. Due to…

人机交互 · 计算机科学 2025-09-01 Simon Burbach , Maria Maleshkova , Florian Centler , Tanja Joan Schmidt

The present paper proposes a novel method of quantification of the variation in biofilm architecture, in correlation with the alteration of growth conditions that include, variations of substrate and conditioning layer. The polymeric…

生物物理 · 物理学 2018-01-30 Suparna Dutta Sinha , Saptarshi Das , Sujata Tarafdar , Tapati Dutta

Short-term physico-chemical reactions at the interface between bioactive glass particles and biological fluids are studied and we focus our attention on the measurements of O/Si atomic ratio. The studied bioactive glass is in the…

生物物理 · 物理学 2007-05-23 V. Blanchet , E. Jallot , J. Michel , L. Wortham , D. Laurent-Maquin , G. Balossier

Understanding the evolution of cellular microenvironments in spatiotemporal data is essential for deciphering tissue development and disease progression. While experimental techniques like spatial transcriptomics now enable high-resolution…

机器学习 · 计算机科学 2025-12-29 Kristiyan Sakalyan , Alessandro Palma , Filippo Guerranti , Fabian J. Theis , Stephan Günnemann

Anaerobic processes (e.g., methanogenesis and fermentation) largely contribute to element cycling and natural contaminant attenuation/mobilization, even in well-oxygenated porous environments, such as shallow aquifers. This paradox is…

生物物理 · 物理学 2022-11-24 Giulia Ceriotti , Sergey M. Borisov , Jasmine Berg , Pietro de Anna

The focus of this paper is the numerical solution of a pore-scale model for the growth of a permeable biofilm. The model includes water flux inside the biofilm, different biofilm components, and shear stress on the biofilm-water interface.…

流体动力学 · 物理学 2020-07-14 David Landa-Marbán , Iuliu S. Pop , Kundan Kumar , Florin A. Radu

We study the time evolution and driven motion of thin liquid films lying on top of chemical patterns on a substrate. Lattice-Boltzmann and molecular dynamics methods are used for simulations of the flow of microscopic and nanoscopic films,…

软凝聚态物质 · 物理学 2012-04-04 Fabian Dörfler , Markus Rauscher , Joel Koplik , Jens Harting , S. Dietrich
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