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Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

计算与语言 · 计算机科学 2024-10-28 Shubham Vatsal , Ayush Singh

Electronic Health Records (EHRs) provide crucial information for clinical decision-making. However, their high-dimensionality, heterogeneity, and sparsity make clinical prediction challenging. Large Language Models (LLMs) allowed progress…

计算与语言 · 计算机科学 2026-01-28 Jesus Lovon-Melgarejo , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

计算与语言 · 计算机科学 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

LLMs are revolutionizing NLP tasks. However, the use of the most advanced LLMs, such as GPT-4, is often prohibitively expensive for most specialized fields. We introduce HEAL, the first continuously trained 13B LLaMA2-based LLM that is…

计算与语言 · 计算机科学 2024-04-05 Dong Yuan , Eti Rastogi , Gautam Naik , Sree Prasanna Rajagopal , Sagar Goyal , Fen Zhao , Bharath Chintagunta , Jeff Ward

Peer review is a critical process for ensuring the integrity of published scientific research. Confidence in this process is predicated on the assumption that experts in the relevant domain give careful consideration to the merits of…

计算与语言 · 计算机科学 2024-12-09 Sungduk Yu , Man Luo , Avinash Madasu , Vasudev Lal , Phillip Howard

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

计算与语言 · 计算机科学 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

As AI-generated health information proliferates online and becomes increasingly indistinguishable from human-sourced information, it becomes critical to understand how people trust and label such content, especially when the information is…

人机交互 · 计算机科学 2025-12-16 Xin Sun , Rongjun Ma , Shu Wei , Pablo Cesar , Jos A. Bosch , Abdallah El Ali

Reference labels for machine-learning benchmarks are increasingly synthesized with LLM assistance, but their reliability remains underexamined. We audit MedCalc-Bench, a clinical benchmark for medical score computation whose labels were…

人工智能 · 计算机科学 2026-04-14 Junze Ye , Daniel Tawfik , Alex J. Goodell , Nikhil V. Kotha , Mark K. Buyyounouski , Mohsen Bayati

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

计算与语言 · 计算机科学 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Health misinformation spreading online poses a significant threat to public health. Researchers have explored methods for automatically generating counterspeech to health misinformation as a mitigation strategy. Existing approaches often…

计算与语言 · 计算机科学 2026-04-03 Xiaoying Song , Anirban Saha Anik , Dibakar Barua , Pengcheng Luo , Junhua Ding , Lingzi Hong

Clinical decision-making in emergency medicine demands rapid, accurate diagnoses under uncertainty. Despite benchmark progress, evidence for LLMs as interactive aids in live physician workflows remains sparse. MedSyn lets physicians…

Personalized text generation is an emerging research area that has attracted much attention in recent years. Most studies in this direction focus on a particular domain by designing bespoke features or models. In this work, we propose a…

计算与语言 · 计算机科学 2023-08-17 Cheng Li , Mingyang Zhang , Qiaozhu Mei , Yaqing Wang , Spurthi Amba Hombaiah , Yi Liang , Michael Bendersky

Instruction tuning has emerged as the key in aligning large language models (LLMs) with specific task instructions, thereby mitigating the discrepancy between the next-token prediction objective and users' actual goals. To reduce the labor…

计算与语言 · 计算机科学 2024-04-10 Zifeng Wang , Chun-Liang Li , Vincent Perot , Long T. Le , Jin Miao , Zizhao Zhang , Chen-Yu Lee , Tomas Pfister

Proprietary Large Language Models (LLMs) such as GPT-4 and Gemini have demonstrated promising capabilities in clinical text summarization tasks. However, due to patient data privacy concerns and computational costs, many healthcare…

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

To enhance the performance of large language models (LLMs) in biomedical natural language processing (BioNLP) by introducing a domain-specific instruction dataset and examining its impact when combined with multi-task learning principles.…

计算与语言 · 计算机科学 2024-06-10 Hieu Tran , Zhichao Yang , Zonghai Yao , Hong Yu

Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that…

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on…

计算与语言 · 计算机科学 2025-10-13 Jie Liu , Wenxuan Wang , Zizhan Ma , Guolin Huang , Yihang SU , Kao-Jung Chang , Wenting Chen , Haoliang Li , Linlin Shen , Michael Lyu

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…