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We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Volumetric magnetic resonance (MR) image segmentation plays an important role in many clinical applications. Deep learning (DL) has recently achieved state-of-the-art or even human-level performance on various image segmentation tasks.…

计算机视觉与模式识别 · 计算机科学 2022-11-17 Yousuf Babiker M. Osman , Cheng Li , Weijian Huang , Nazik Elsayed , Zhenzhen Xue , Hairong Zheng , Shanshan Wang

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

医学物理 · 物理学 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

The segmentation of prostate whole gland and transition zone in Diffusion Weighted MRI (DWI) are the first step in designing computer-aided detection algorithms for prostate cancer. However, variations in MRI acquisition parameters and…

图像与视频处理 · 电气工程与系统科学 2020-10-29 Saman Motamed , Isha Gujrathi , Dominik Deniffel , Anton Oentoro , Masoom A. Haider , Farzad Khalvati

Prostate gland segmentation from T2-weighted MRI is a critical yet challenging task in clinical prostate cancer assessment. While deep learning-based methods have significantly advanced automated segmentation, most conventional…

图像与视频处理 · 电气工程与系统科学 2025-06-25 Ahmad Mustafa , Reza Rastegar , Ghassan AlRegib

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

医学物理 · 物理学 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

The diagnosis of prostate cancer increasingly depends on multimodal imaging, particularly magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS). However, accurate registration between these modalities remains a fundamental…

图像与视频处理 · 电气工程与系统科学 2025-06-03 Xudong Ma , Nantheera Anantrasirichai , Stefanos Bolomytis , Alin Achim

Prostate cancer (PCa) is a severe disease among men globally. It is important to identify PCa early and make a precise diagnosis for effective treatment. For PCa diagnosis, Multi-parametric magnetic resonance imaging (mpMRI) emerged as an…

图像与视频处理 · 电气工程与系统科学 2023-10-11 Anil B. Gavade , Neel Kanwal , Priyanka A. Gavade , Rajendra Nerli

Automatic segmentation of medical images with DL algorithms has proven to be highly successful. With most of these algorithms, inter-observer variation is an acknowledged problem, leading to sub-optimal results. This problem is even more…

Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

图像与视频处理 · 电气工程与系统科学 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

医学物理 · 物理学 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

医学物理 · 物理学 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

Recently, deep learning (DL) has automated and accelerated the clinical radiation therapy (RT) planning significantly by predicting accurate dose maps. However, most DL-based dose map prediction methods are data-driven and not applicable…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Jie Zeng , Zeyu Han , Xingchen Peng , Jianghong Xiao , Peng Wang , Yan Wang

Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover,…

图像与视频处理 · 电气工程与系统科学 2024-11-06 Robin Trombetta , Olivier Rouvière , Carole Lartizien

The MR-Linac can enable real-time radiotherapy adaptation. However, real-time image acquisition is restricted to 2D to obtain sufficient spatial resolution, hindering accurate 3D segmentation. By reducing spatial resolution fast 3D imaging…

医学物理 · 物理学 2023-10-18 Samuel Fransson , David Tilly , Robin Strand

The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to…

计算机视觉与模式识别 · 计算机科学 2021-01-19 Eleni Chiou , Francesco Giganti , Shonit Punwani , Iasonas Kokkinos , Eleftheria Panagiotaki