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In this study, recommendations of the AAPM TG- 43 (U1) report have been followed to characterize the new 192Ir pulse dose rate source, provided by the Applied Radiation Research School, Nuclear Science and Technology Research Institute in…

Purpose: Many planning methods for high dose rate (HDR) brachytherapy treatment planning require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose…

医学物理 · 物理学 2016-11-25 Timmy Siauw , Adam Cunha , Alper Atamturk , I-Chow Hsu , Jean Pouliot , Ken Goldberg

Purpose: To develop clinically relevant test cases for commissioning Model-Based Dose Calculation Algorithms (MBDCAs) for 192Ir High Dose Rate (HDR) gynecologic brachytherapy following the workflow proposed by the TG-186 report and the…

医学物理 · 物理学 2026-01-27 V. Peppa , M. Robitaille , F. Akbari , S. A. Enger , R. M. Thomson , F. Mourtada , G. P. Fonseca

This study presents the development and validation of an independent software tool based on the Varian Eclipse Scripting API (ESAPI) for multi-modal brachytherapy Quality Assurance (QA). The tool addresses GEC-ESTRO HDR protocols and LDR…

医学物理 · 物理学 2026-03-24 J. A. Valgoma

Purpose: To develop a model to generate volumetric dose distribution from two isodose surfaces (iso-surfaces), and to interactively tune dose distribution by iso-surface dragging. Methods: We model volumetric dose distribution as analytical…

医学物理 · 物理学 2022-03-01 Lin Ma , Mingli Chen , Xuejun Gu , Weiguo Lu

The purpose of this work is to develop viable procedures for verifying the applicability of personalized dosimetry in computed tomography (CT) using Monte Carlo-based simulations. Mobile equipment together with customized software was…

Purpose: To verify dose delivery and quality assurance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Method: The Imaging and Radiation Oncology Core Houston (IROC-H) head and neck phantom with thermo- luminescent…

Purpose: We sought to evaluate the feasibility of using machine learning algorithms for multipoint plastic scintillator detector calibration in high-dose-rate brachytherapy. Methods: The dosimetry system consisted of an optimized 1-mm-core…

This study aims to introduce IViST (In Vivo Source Tracking), a novel multi-sensors dosimetry platform for real-time treatment monitoring in HDR brachytherapy. IViST is a platform that comprises 3 parts: 1) an optimized and characterized…

医学物理 · 物理学 2020-06-16 Haydee M. Linares Rosales , Audrey Cantin , Sylviane Aubin , Sam Beddar , Luc Beaulieu

Purpose: To develop and evaluate DosimeTron, an agentic AI system for automated patient-specific MC internal radiation dosimetry in PET/CT examinations. Materials and Methods: In this retrospective study, DosimeTron was evaluated on a…

医学物理 · 物理学 2026-04-09 Eleftherios Tzanis , Michail E. Klontzas , Antonios Tzortzakakis

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

医学物理 · 物理学 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

An MRI-only adaptive radiotherapy (ART) workflow is desirable for managing interfractional changes in anatomy, but producing synthetic CT (sCT) data through paired data-driven deep learning (DL) for abdominal dose calculations remains a…

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

医学物理 · 物理学 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

The $^{192}$Ir sources are widely used for high dose rate (HDR) brachytherapy treatments. The aim of this study is to simulate $^{192}$Ir MicroSelectron v2 HDR brachytherapy source and calculate the air kerma strength, dose rate constant,…

医学物理 · 物理学 2016-01-14 Hamza Naeem , Chaobin Chen , Huaqing Zheng , Ruifen Cao , Xi Pei , Liqin Hu , Yican Wu

Objective: This study aims to develop and validate a novel framework, iPhantom, for automated creation of patient-specific phantoms or digital-twins (DT) using patient medical images. The framework is applied to assess radiation dose to…

Purpose: To present the performance of a multi-point plastic scintillation detector (mPSD) as a tool in vivo dosimetry in brachytherapy. Methods: A previously optimized three-point sensor system was used for in vivo HDR brachytherapy…

医学物理 · 物理学 2021-01-27 Haydee M. Linares Rosales , Louis Archambault , Sam Beddar , Luc Beaulieu

Purpose: To provide a fast computational method, based on the proximal graph solver (POGS) - a convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating…

医学物理 · 物理学 2018-02-07 Myung Cho , Xiaodong Wu , Hossein Dakhah , Jirong Yi , Ryan T. Flynn , Yusung Kim , Weiyu Xu

In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…

医学物理 · 物理学 2022-09-21 A. Asadi , A. Akhavanallaf , S. A. Hosseini , H. Zaidi

Purpose: To validate the accuracy of 4D Monte Carlo (4DMC) simulations to calculate dose deliveries to a deforming anatomy in the presence of realistic respiratory motion traces. A previously developed deformable lung phantom comprising an…

医学物理 · 物理学 2023-05-04 Sara Gholampourkashi , Joanna E. Cygler , Bernie Lavigne , Emily Heath

To accurately verify the dose of intensity-modulated radiation therapy (IMRT), we have used a global optimization method to investigate a new dose-verification algorithm. In practical application of this quality assurance (QA) procedure,…

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