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We study the problem of learning to choose from m discrete treatment options (e.g., news item or medical drug) the one with best causal effect for a particular instance (e.g., user or patient) where the training data consists of passive…

机器学习 · 统计学 2017-08-02 Nathan Kallus

Motivation: Drug combination is a sensible strategy for disease treatment by improving the efficacy and reducing concomitant side effects. Due to the large number of possible combinations among candidate compounds, exhaustive screening is…

定量方法 · 定量生物学 2020-02-26 Liang Yu , Mingfei Xia , Lin Gao

The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

生物大分子 · 定量生物学 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

Time series modeling is crucial for many applications, however, it faces challenges such as complex spatio-temporal dependencies and distribution shifts in learning from historical context to predict task-specific outcomes. To address these…

人工智能 · 计算机科学 2024-08-28 Chidaksh Ravuru , Sagar Srinivas Sakhinana , Venkataramana Runkana

In recent years, many studies extract aspects from user reviews and integrate them with ratings for improving the recommendation performance. The common aspects mentioned in a user's reviews and a product's reviews indicate indirect…

信息检索 · 计算机科学 2019-04-18 Xinyu Guan , Zhiyong Cheng , Xiangnan He , Yongfeng Zhang , Zhibo Zhu , Qinke Peng , Tat-Seng Chua

Federated Learning (FL) allows the training of deep neural networks in a distributed and privacy-preserving manner. However, this concept suffers from malfunctioning updates sent by the attending clients that cause global model performance…

机器学习 · 计算机科学 2025-08-05 Mirko Konstantin , Moritz Fuchs , Anirban Mukhopadhyay

Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook…

应用统计 · 统计学 2019-10-03 Shih-Ting Huang , Yannick Düren , Kristoffer H. Hellton , Johannes Lederer

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

信息检索 · 计算机科学 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Interpretability is a desirable property of ITRs, as it helps…

统计方法学 · 统计学 2023-11-06 Jacob M. Maronge , Jared D. Huling , Guanhua Chen

Recommender Systems are an integral part of music sharing platforms. Often the aim of these systems is to increase the time, the user spends on the platform and hence having a high commercial value. The systems which aim at increasing the…

信息检索 · 计算机科学 2018-11-21 Noveen Sachdeva , Kartik Gupta , Vikram Pudi

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

计算与语言 · 计算机科学 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

定量方法 · 定量生物学 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

人工智能 · 计算机科学 2025-09-16 Susanta Mitra

Interfractional geometric uncertainties can lead to deviations of the actual delivered dose from the prescribed dose distribution. To better handle these uncertainties during treatment, the authors propose a dynamic framework for robust…

医学物理 · 物理学 2019-05-16 Michelle Böck , Kjell Eriksson , Anders Forsgren

Evidence suggests that medication adherence applications (apps) are one of the most effective methods to remind patients to take medication on time. Reminders via apps are overwhelming today, consumers discard using them after a brief…

人机交互 · 计算机科学 2023-10-24 Nawal Chanane , Farhaan Mirza , M. Asif Naeem

Interactive conversational recommender systems have gained significant attention for their ability to capture user preferences through natural language interactions. However, existing approaches face substantial challenges in handling…

人工智能 · 计算机科学 2025-10-03 Bo Ma , Hang Li , ZeHua Hu , XiaoFan Gui , LuYao Liu , Simon Lau

Machine Learning's proliferation in critical fields such as healthcare, banking, and criminal justice has motivated the creation of tools which ensure trust and transparency in ML models. One such tool is Actionable Recourse (AR) for…

机器学习 · 计算机科学 2023-09-07 Jayanth Yetukuri , Ian Hardy , Yang Liu

Medication recommendation targets to provide a proper set of medicines according to patients' diagnoses, which is a critical task in clinics. Currently, the recommendation is manually conducted by doctors. However, for complicated cases,…

机器学习 · 计算机科学 2022-02-21 Rui Wu , Zhaopeng Qiu , Jiacheng Jiang , Guilin Qi , Xian Wu

While large reasoning models demonstrate strong performance on complex tasks, they lack the ability to adjust reasoning token usage based on task difficulty. This often leads to the "overthinking" problem -- excessive and unnecessary…

计算与语言 · 计算机科学 2025-10-14 Siye Wu , Jian Xie , Yikai Zhang , Aili Chen , Kai Zhang , Yu Su , Yanghua Xiao

We describe and study a model for an Automated Online Recommendation System (AORS) in which a user's preferences can be time-dependent and can also depend on the history of past recommendations and play-outs. The three key features of the…

机器学习 · 计算机科学 2016-03-31 Rahul Meshram , Aditya Gopalan , D. Manjunath