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Retrieval-Augmented Generation (RAG) is increasingly employed in generative AI-driven scientific workflows to integrate rapidly evolving scientific knowledge bases, yet its reliability is frequently compromised by non-determinism in their…

分布式、并行与集群计算 · 计算机科学 2025-09-24 Baiqiang Wang , Dongfang Zhao , Nathan R Tallent , Luanzheng Guo

Recent studies have shown that the majority of published computational models in systems biology and physiology are not repeatable or reproducible. There are a variety of reasons for this. One of the most likely reasons is that given how…

其他定量生物学 · 定量生物学 2021-07-13 Herbert M. Sauro

There are phenomena that cannot be measured without subjective testing. However, subjective testing is a complex issue with many influencing factors. These interplay to yield either precise or incorrect results. Researchers require a tool…

多媒体 · 计算机科学 2020-09-29 Jakub Nawała , Lucjan Janowski , Bogdan Ćmiel , Krzysztof Rusek

Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative…

应用统计 · 统计学 2011-10-24 Qunhua Li , James B. Brown , Haiyan Huang , Peter J. Bickel

Existing research on merging behavior generally prioritize the application of various algorithms, but often overlooks the fine-grained process and analysis of trajectories. This leads to the neglect of surrounding vehicle matching, the…

机器人学 · 计算机科学 2023-03-22 Yang Li , Yang Liu , Daiheng Ni , Ang Ji , Linbo Li , Yajie Zou

The replicability crisis has drawn attention to numerous weaknesses in psychology and social science research practice. In this work we focus on three issues that cannot be addressed with replication alone, and which deserve more attention:…

应用统计 · 统计学 2021-07-16 Matthew J. Vowels

A common problem in health research is that we have a large database with many variables measured on a large number of individuals. We are interested in measuring additional variables on a subsample; these measurements may be newly…

统计方法学 · 统计学 2022-03-22 Thomas Lumley , Tong Chen

The field of psychological sciences has been grappling with the replicability crisis. Various issues have been identified as potential sources of this problem. We bring to light a potential source that has largely been overlooked and…

统计方法学 · 统计学 2025-04-28 Yoav Zeevi , Sofi Astashenko , Liad Mudrik , Yoav Benjamini

"How to evaluate the de novo designs proposed by a generative model?" Despite the transformative potential of generative deep learning in drug discovery, this seemingly simple question has no clear answer. The absence of standardized…

生物大分子 · 定量生物学 2025-11-14 Rıza Özçelik , Francesca Grisoni

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

统计方法学 · 统计学 2023-05-11 Lorenzo Masoero , Emma Thomas , Giovanni Parmigiani , Svitlana Tyekucheva , Lorenzo Trippa

There has been increasing concern within the machine learning community that we are in a reproducibility crisis. As many have begun to work on this problem, all work we are aware of treat the issue of reproducibility as an intrinsic binary…

机器学习 · 统计学 2020-12-21 Edward Raff

Multi-class classification problem is among the most popular and well-studied statistical frameworks. Modern multi-class datasets can be extremely ambiguous and single-output predictions fail to deliver satisfactory performance. By allowing…

机器学习 · 统计学 2021-02-25 Evgenii Chzhen , Christophe Denis , Mohamed Hebiri , Titouan Lorieul

Reinforcement learning faces significant challenges when applied to tasks characterized by sparse reward structures. Although imitation learning, within the domain of supervised learning, offers faster convergence, it relies heavily on…

机器学习 · 计算机科学 2025-09-04 Zeqiang Zhang , Fabian Wurzberger , Gerrit Schmid , Sebastian Gottwald , Daniel A. Braun

The replicability crisis is a major issue across nearly all areas of empirical science, calling for the formal study of replicability in statistics. Motivated in this context, [Impagliazzo, Lei, Pitassi, and Sorrell STOC 2022] introduced…

机器学习 · 统计学 2024-06-06 Max Hopkins , Russell Impagliazzo , Daniel Kane , Sihan Liu , Christopher Ye

The integration of machine learning techniques in materials discovery has become prominent in materials science research and has been accompanied by an increasing trend towards open-source data and tools to propel the field. Despite the…

材料科学 · 物理学 2026-05-27 Daniel Persaud , Logan Ward , Jason Hattrick-Simpers

Targeted Learning is a subfield of statistics that unifies advances in causal inference, machine learning and statistical theory to help answer scientifically impactful questions with statistical confidence. Targeted Learning is driven by…

An essential part of research and scientific communication is researchers' ability to reproduce the results of others. While there have been increasing standards for authors to make data and code available, many of these files are hard to…

数字图书馆 · 计算机科学 2021-09-23 Layan Bahaidarah , Ethan Hung , Andreas F. De Melo Oliveira , Jyotsna Penumaka , Lukas Rosario , Ana Trisovic

Graph neural networks (GNNs) have witnessed an unprecedented proliferation in tackling several problems in computer vision, computer-aided diagnosis, and related fields. While prior studies have focused on boosting the model accuracy,…

机器学习 · 计算机科学 2021-09-07 Mohammed Amine Gharsallaoui , Islem Rekik

Reproducibility of computationally-derived scientific discoveries should be a certainty. As the product of several person-years' worth of effort, results -- whether disseminated through academic journals, conferences or exploited through…

计算工程、金融与科学 · 计算机科学 2015-06-17 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

The field of deep learning has witnessed significant breakthroughs, spanning various applications, and fundamentally transforming current software capabilities. However, alongside these advancements, there have been increasing concerns…

机器学习 · 计算机科学 2025-05-07 Nikita Ravi , Abhinav Goel , James C. Davis , George K. Thiruvathukal