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Whole-slide image (WSI) analysis is challenging due to the gigapixel scale of slides and their inherent hierarchical multi-resolution structure. Existing multiple instance learning (MIL) approaches often model WSIs as unordered collections…

计算机视觉与模式识别 · 计算机科学 2026-03-09 Dongqing Xie , Yonghuang Wu

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

计算机视觉与模式识别 · 计算机科学 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

机器学习 · 计算机科学 2018-07-09 Shabnam Ghaffarzadegan

Universal models for medical image segmentation, such as interactive and in-context learning (ICL) models, offer strong generalization but require extensive annotations. Interactive models need repeated user prompts for each image, while…

计算机视觉与模式识别 · 计算机科学 2025-10-09 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Jinyan Zhou , Jianfeng Cao , Hanyang Peng , Ting Ma

\textit{Multiple Instance Learning} (MIL) is concerned with learning from bags of instances, where only bag labels are given and instance labels are unknown. Existent approaches in this field were mainly designed for the bag-level label…

机器学习 · 计算机科学 2019-05-30 Minlong Peng , Qi Zhang

In the last years, the weakly supervised paradigm of multiple instance learning (MIL) has become very popular in many different areas. A paradigmatic example is computational pathology, where the lack of patch-level labels for whole-slide…

计算机视觉与模式识别 · 计算机科学 2023-10-31 Pablo Morales-Álvarez , Arne Schmidt , José Miguel Hernández-Lobato , Rafael Molina

Multiple instance learning (MIL) is a form of weakly supervised learning where training instances are arranged in sets, called bags, and a label is provided for the entire bag. This formulation is gaining interest because it naturally fits…

计算机视觉与模式识别 · 计算机科学 2022-05-10 Marc-André Carbonneau , Veronika Cheplygina , Eric Granger , Ghyslain Gagnon

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

定量方法 · 定量生物学 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

Multi-modal class-incremental learning (MMCIL) seeks to leverage multi-modal data, such as audio-visual and image-text pairs, thereby enabling models to learn continuously across a sequence of tasks while mitigating forgetting. While…

机器学习 · 计算机科学 2025-01-17 Xianghu Yue , Yiming Chen , Xueyi Zhang , Xiaoxue Gao , Mengling Feng , Mingrui Lao , Huiping Zhuang , Haizhou Li

Weakly-supervised audio-visual violence detection aims to distinguish snippets containing multimodal violence events with video-level labels. Many prior works perform audio-visual integration and interaction in an early or intermediate…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Jiashuo Yu , Jinyu Liu , Ying Cheng , Rui Feng , Yuejie Zhang

Multiple instance learning (MIL) is concerned with learning from sets (bags) of objects (instances), where the individual instance labels are ambiguous. In this setting, supervised learning cannot be applied directly. Often, specialized MIL…

机器学习 · 统计学 2014-12-04 Veronika Cheplygina , David M. J. Tax , Marco Loog

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

计算机视觉与模式识别 · 计算机科学 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Multiple Instance Learning (MIL) has emerged as a dominant paradigm to extract discriminative feature representations within Whole Slide Images (WSIs) in computational pathology. Despite driving notable progress, existing MIL approaches…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Shu Yang , Yihui Wang , Hao Chen

Computer-aided Whole Slide Image (WSI) classification has the potential to enhance the accuracy and efficiency of clinical pathological diagnosis. It is commonly formulated as a Multiple Instance Learning (MIL) problem, where each WSI is…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Linhao Qu , Shiman Li , Xiaoyuan Luo , Shaolei Liu , Qinhao Guo , Manning Wang , Zhijian Song

Computational pathology (CPath) has significantly advanced the clinical practice of pathology. Despite the progress made, Multiple Instance Learning (MIL), a promising paradigm within CPath, continues to face challenges, particularly…

计算机视觉与模式识别 · 计算机科学 2024-08-28 Yuqi Zhang , Xiaoqian Zhang , Jiakai Wang , Yuancheng Yang , Taiying Peng , Chao Tong

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

Multi-instance multi-label (MIML) learning is widely applicated in numerous domains, such as the image classification where one image contains multiple instances correlated with multiple logic labels simultaneously. The related labels in…

计算机视觉与模式识别 · 计算机科学 2023-04-24 Houcheng Su , Jintao Huang , Daixian Liu , Rui Yan , Jiao Li , Chi-man Vong

Class Incremental Learning (CIL) aims to sequentially learn new classes while avoiding catastrophic forgetting of previous knowledge. We propose to use Masked Autoencoders (MAEs) as efficient learners for CIL. MAEs were originally designed…

计算机视觉与模式识别 · 计算机科学 2023-08-25 Jiang-Tian Zhai , Xialei Liu , Andrew D. Bagdanov , Ke Li , Ming-Ming Cheng

Weakly supervised multiple instance learning (MIL) is a challenging task given that only bag-level labels are provided, while each bag typically contains multiple instances. This topic has been extensively studied in histopathological image…

计算机视觉与模式识别 · 计算机科学 2025-08-01 Bodong Zhang , Hamid Manoochehri , Xiwen Li , Beatrice S. Knudsen , Tolga Tasdizen
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