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The problem of optimization of propagation-based phase-contrast imaging setups is considered in the case of projection X-ray imaging and three-dimensional tomography with phase retrieval. For two-dimensional imaging, a simple model for a…

医学物理 · 物理学 2026-03-03 T. E. Gureyev , D. M. Paganin , H. M. Quiney

Signal-to-noise ratio and spatial resolution are quantitatively analysed in the context of in-line (propagation based) X-ray phase-contrast imaging. It is known that free-space propagation of a coherent X-ray beam from the imaged object to…

医学物理 · 物理学 2023-12-20 T. E. Gureyev , D. M. Paganin , H. M. Quiney

A propagation-based x-ray phase-contrast imaging (PBI) setup using a conventional x-ray source (LFF Cu target) is presented. A virtual x-ray source of 40 x 50 $\mu$$m^2$ was created by using, horizontally, a $6^o$ take-off angle (with the…

其他凝聚态物理 · 物理学 2007-10-08 M. G. Hönnicke , E. M. Kakuno , J. Manica , C. Cusatis

Propagation-based phase-contrast X-ray imaging (PB-PCXI) generates image contrast by utilizing sample-imposed phase-shifts. This has proven useful when imaging weakly-attenuating samples, as conventional attenuation-based imaging does not…

Paganin's method for image reconstruction in propagation-based phase-contrast X-ray imaging and tomography has enjoyed broad acceptance in recent years, with over one thousand publications citing its use. The present paper discusses…

医学物理 · 物理学 2026-01-13 Timur E. Gureyev , David M. Paganin , Ashkan Pakzad , Harry M. Quiney

A simple coherent-imaging method due to Paganin et al. is widely employed for phase-amplitude reconstruction of samples using a single paraxial x-ray propagation-based phase-contrast image. The method assumes that the sample-to-detector…

Propagation-based X-ray phase-contrast imaging (PBI) enables high-contrast visualization of lung structures and holds strong medical potential. However, safe translation to the clinic will require a substantial radiation dose reduction,…

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

图像与视频处理 · 电气工程与系统科学 2019-02-28 David M. Paganin , Daniele Pelliccia

Many lung diseases require detailed visualisation for accurate diagnosis and treatment. High-resolution computed tomography (CT) is the gold-standard technique for non-invasive lung disease detection, but it presents a risk to the patient…

Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

量子物理 · 物理学 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera

Portable backscatter imaging systems (PBI) integrate an X-ray source and detector in a single unit, utilizing Compton scattering photons to rapidly acquire superficial or shallow structural information of an inspected object through…

图像与视频处理 · 电气工程与系统科学 2026-02-13 Linxuan Li , Wenjia Wei , Yunfei Lu , Wenwen Zhang , Yanlong Zhang , Wei Zhao

Imaging is an important means by which information is gathered regarding the physical world. Spatial resolution and signal-to-noise ratio are underpinning concepts. There is a paucity of rigorous definitions for these quantities, which are…

光学 · 物理学 2019-09-27 David M. Paganin , Alexander Kozlov , Timur E. Gureyev

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

光学 · 物理学 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

The following paper describes a method for three-dimensional (3D) reconstruction of multi-material objects based on propagation-based X-ray phase-contrast tomography (PB-CT) with phase retrieval using the homogenous form of the…

医学物理 · 物理学 2022-05-25 Darren Thompson , Yakov I. Nesterets , Konstantin M. Pavlov , Timur Gureyev

The ill-posed problem of phase retrieval in optics, using one or more intensity measurements, has a multitude of applications using electromagnetic or matter waves. Many phase retrieval algorithms are computed on pixel arrays using discrete…

图像与视频处理 · 电气工程与系统科学 2022-09-21 J. A. Pollock , K. S. Morgan , L. C. P. Croton , M. K. Croughan , G. Ruben , N. Yagi , H. Sekiguchi , M. J. Kitchen

Propagation-based neutron phase-contrast tomography was demonstrated using the ISIS pulsed spallation source. The proof-of-concept tomogram with Paganin-type phase-retrieval filter applied exhibited an effective net boost of $23\pm 1$ in…

图像与视频处理 · 电气工程与系统科学 2023-07-31 David M. Paganin , Morten Sales , Peter M. Kadletz , Winfried Kockelmann , Mario A. Beltran , Henning F. Poulsen , Søren Schmidt

Digital image plays a vital role in the early detection of cancers, such as prostate cancer, breast cancer, lungs cancer, cervical cancer. Ultrasound imaging method is also suitable for early detection of the abnormality of fetus. The…

计算机视觉与模式识别 · 计算机科学 2022-04-21 Vidhi Rawat , Alok Jain , Vibhakar Shrimali

A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real…

医学物理 · 物理学 2021-11-16 T. E. Gureyev , D. M. Paganin , B. Arhatari , S. T. Taba , S. Lewis , P. C. Brennan , H. M. Quiney

We demonstrate the use of a phase retrieval technique for propagation-based phase contrast neutron imaging with a polychromatic beam. This enables imaging samples with low absorption contrast and/or improving the signal-to-noise ratio to…

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