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The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…

细胞行为 · 定量生物学 2023-06-30 Sebastian Aland , Claudia Wohlgemuth

Lubrication forces depend to a high degree on elasticity, texture, charge, chemistry, and temperature of the interacting surfaces. Therefore, by appropriately designing surface properties, we may tailor lubrication forces to reduce…

软凝聚态物质 · 物理学 2020-08-19 Aidan Rinehart , Uǧis L{ā}cis , Thomas Salez , Shervin Bagheri

Bacteria in aquatic environments often interact with particulate matter. A key example is bacterial degradation of marine snow responsible for carbon export from the upper ocean in the biological pump. The ecological interaction between…

The structure of polymers at solid interfaces evolves over time, but the corresponding changes in their rheological properties remain poorly understood. Here, using a home-built quartz tuning fork atomic force microscope-based…

流体动力学 · 物理学 2025-08-22 Jaewon Shim , Manhee Lee , Wonho Jhe

Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…

The lubricated motion of an object near a deformable boundary presents striking subtleties arising from the coupling between the elasticity of the boundary and lubricated flow, including but not limited to the emergence of a lift force…

软凝聚态物质 · 物理学 2025-10-08 Aditya Jha , Yacine Amarouchene , Thomas Salez

In the present work we simulate the basic two-dimensional dynamics of swarming E. coli bacteria on the surface of a moderately soft agar plate. Individual bacteria are modelled by self-propelled ridged bodies (agents), which interact with…

软凝聚态物质 · 物理学 2016-12-31 David Hansmann , Guido Fier , Rubén Carlos Buceta

It is well established that the parasites of the genus Leishmania exhibit complex surface interactions with the sandfly vector midgut epithelium, but no prior study has considered the details of their hydrodynamics. Here, the boundary…

生物物理 · 物理学 2018-12-10 Benjamin J. Walker , Richard J. Wheeler , Kenta Ishimoto , Eamonn A. Gaffney

We analyse the motion of a flagellated bacterium in a two-fluid medium using slender body theory. The two-fluid model is useful for describing a body moving through a complex fluid with a microstructure whose length scale is comparable to…

流体动力学 · 物理学 2024-12-11 Sabarish V. Narayanan , Donald L. Koch , Sarah Hormozi

Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of…

生物物理 · 物理学 2019-05-29 Rachel Mok , Jörn Dunkel , Vasily Kantsler

Confinement and wall effects are known to affect the kinematics and propulsive characteristics of swimming microorganisms. When a solid body is dragged through a viscous fluid at constant velocity, the presence of a wall increases fluid…

生物物理 · 物理学 2010-10-29 Arthur A. Evans , Eric Lauga

We present a multi-scale model to study the attachment of spherical particles with a rigid core, coated with binding ligands and in equilibrium with the surrounding, quiescent fluid medium. This class of fluid-immersed adhesion is…

生物物理 · 物理学 2013-09-10 Sarthok Sircar , John G. Younger , David M. Bortz

Concentrated suspensions of swimming microorganisms and other forms of active matter are known to display complex, self-organized spatio-temporal patterns on scales large compared to those of the individual motile units. Despite intensive…

软凝聚态物质 · 物理学 2014-07-15 Enkeleida Lushi , Hugo Wioland , Raymond E Goldstein

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

软凝聚态物质 · 物理学 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

Phagocytosis is the process by which cells, which are 5 to 10 times larger than the particle size, engulf particles, holding substantial importance in various biological contexts ranging from the nutrient uptake of unicellular organisms to…

软凝聚态物质 · 物理学 2024-11-20 Partha Sarathi Mondal , Pawan Kumar Mishra , Mitali Thorat , Ananya Verma , Shradha Mishra

We have devised an original laboratory experiment where we investigate the frictional behaviour of a single crystal salt slider over a large number of deformation cycles. Because of its physical properties, salt, a surrogate for natural…

材料科学 · 物理学 2015-06-25 Christophe Voisin , Francois Renard , Jean-Robert Grasso

A simple solid-on-solid model, proposed earlier to describe overlayer-induced faceting of bcc(111) surface, is applied to faceting of spherical surfaces covered by adsorbate monolayer. Monte Carlo simulation results show that morphology of…

软凝聚态物质 · 物理学 2009-11-11 Daniel Niewieczerzal , Czeslaw Oleksy

Biofilms are communities of bacteria adhered to surfaces. Recently, biofilms of rod-shaped bacteria were observed at single-cell resolution and shown to develop from a disordered, two-dimensional layer of founder cells into a…

The basic process of the innate immune system when phagocyte (white blood cell) engulf or swallow a target particle (bacterium or dead cell), is called phagocytosis. We apply the phase field approach in the spirit of [1], that couples the…

生物物理 · 物理学 2021-11-15 Mohammad Abu Hamed , Alexander A. Nepomnyashchy

In this work we introduce a stochastic model to describe directional changes in the movement of swimming bacteria. We use the probability density function (PDF) of turn angles, measured on tumbling wild-type {\it E. coli}, to build a…

软凝聚态物质 · 物理学 2017-07-13 G. Fier , D. Hansmann , R. C. Buceta