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Vision Language Models (VLMs) like CLIP have attracted substantial attention in pathology, serving as backbones for applications such as zero-shot image classification and Whole Slide Image (WSI) analysis. Additionally, they can function as…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Yuxuan Sun , Yunlong Zhang , Yixuan Si , Chenglu Zhu , Zhongyi Shui , Kai Zhang , Jingxiong Li , Xingheng Lyu , Tao Lin , Lin Yang

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

图像与视频处理 · 电气工程与系统科学 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Whole-slide image analysis is essential for diagnostic tasks in pathology, yet existing deep learning methods primarily rely on flat classification, ignoring hierarchical relationships among class labels. In this study, we propose HiClass,…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Keunho Byeon , Jinsol Song , Seong Min Hong , Yosep Chong , Jin Tae Kwak

Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H\&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Min Cen , Zhenfeng Zhuang , Yuzhe Zhang , Min Zeng , Baptiste Magnier , Lequan Yu , Hong Zhang , Liansheng Wang

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

图像与视频处理 · 电气工程与系统科学 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating…

图像与视频处理 · 电气工程与系统科学 2023-03-06 Shaheer U. Saeed , Tom Syer , Wen Yan , Qianye Yang , Mark Emberton , Shonit Punwani , Matthew J. Clarkson , Dean C. Barratt , Yipeng Hu

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

机器学习 · 计算机科学 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

图像与视频处理 · 电气工程与系统科学 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Ruicheng Yuan , Zhenxuan Zhang , Anbang Wang , Liwei Hu , Xiangqian Hua , Yaya Peng , Jiawei Luo , Guang Yang

Brain CT report generation is significant to aid physicians in diagnosing cranial diseases. Recent studies concentrate on handling the consistency between visual and textual pathological features to improve the coherence of report. However,…

计算机视觉与模式识别 · 计算机科学 2024-10-02 Chengxin Zheng , Junzhong Ji , Yanzhao Shi , Xiaodan Zhang , Liangqiong Qu

Integrating artificial intelligence (AI) with healthcare data is rapidly transforming medical diagnostics and driving progress toward precision medicine. However, effectively leveraging multimodal data, particularly digital pathology whole…

图像与视频处理 · 电气工程与系统科学 2025-12-15 Areej Alsaafin , Abubakr Shafique , Saghir Alfasly , Krishna R. Kalari , H. R. Tizhoosh

Existing deep learning methods for radiology report generation enhance diagnostic efficiency but often overlook physician-informed medical priors. This leads to a suboptimal alignment between the structured explanations and disease…

组织与器官 · 定量生物学 2026-04-13 Aishik Konwer , Moinak Bhattacharya , Prateek Prasanna

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

Personalized diagnoses have not been possible due to sear amount of data pathologists have to bear during the day-to-day routine. This lead to the current generalized standards that are being continuously updated as new findings are…

计算机视觉与模式识别 · 计算机科学 2021-10-27 Jialun Wu , Zeyu Gao , Haichuan Zhang , Ruonan Zhang , Tieliang Gong , Chunbao Wang , Chen Li

Accurate classification of Whole Slide Images (WSIs) and Regions of Interest (ROIs) is a fundamental challenge in computational pathology. While mainstream approaches often adopt Multiple Instance Learning (MIL), they struggle to capture…

计算机视觉与模式识别 · 计算机科学 2025-08-08 Mingxi Fu , Xitong Ling , Yuxuan Chen , Jiawen Li , fanglei fu , Huaitian Yuan , Tian Guan , Yonghong He , Lianghui Zhu

Cancer pathological analysis requires modeling tumor heterogeneity across multiple modalities, primarily through transcriptomics and whole slide imaging (WSI), along with their spatial relations. On one hand, bulk transcriptomics and WSI…

机器学习 · 计算机科学 2026-03-17 Jingkun Yu , Guangkai Shang , Changtao Li , Xun Gong , Tianrui Li , Yazhou He , Zhipeng Luo

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

图像与视频处理 · 电气工程与系统科学 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu