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We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

神经元与认知 · 定量生物学 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

计算机视觉与模式识别 · 计算机科学 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

A task-specific model trained on 212,231 UK Biobank subjects to predict vascular age from PPG (AI-PPG Age) fails on a different clinical population: predictions collapse to a narrow 38-67 year range regardless of true age. Meanwhile, a…

机器学习 · 计算机科学 2026-03-17 N. Brag

Naked eye recognition of age is usually based on comparison with the age of others. However, this idea is ignored by computer tasks because it is difficult to obtain representative contrast images of each age. Inspired by the transfer…

计算机视觉与模式识别 · 计算机科学 2023-03-15 Ping Chen , Xingpeng Zhang , Ye Li , Ju Tao , Bin Xiao , Bing Wang , Zongjie Jiang

Background: Accurate survival time estimates aid end-of-life medical decision-making. Objectives: Develop an interpretable survival model for elderly residential aged care residents using advanced machine learning. Setting: A major…

机器学习 · 计算机科学 2023-12-11 Teo Susnjak , Elise Griffin

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

Purpose: Hard-to-interpret Black-box Machine Learning (ML) were often used for early Alzheimer's Disease (AD) detection. Methods: To interpret eXtreme Gradient Boosting (XGBoost), Random Forest (RF), and Support Vector Machine (SVM)…

机器学习 · 计算机科学 2022-11-08 Louise Bloch , Christoph M. Friedrich

While utilizing machine learning models, one of the most crucial aspects is how bias and fairness affect model outcomes for diverse demographics. This becomes especially relevant in the context of machine learning for medical imaging…

图像与视频处理 · 电气工程与系统科学 2023-10-19 Mahsa Dibaji , Neha Gianchandani , Akhil Nair , Mansi Singhal , Roberto Souza , Mariana Bento

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

图像与视频处理 · 电气工程与系统科学 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap

Objectives: Age and gender estimation is crucial for various applications, including forensic investigations and anthropological studies. This research aims to develop a predictive system for age and gender estimation in living individuals,…

In this paper, we address the problem of apparent age estimation. Different from estimating the real age of individuals, in which each face image has a single age label, in this problem, face images have multiple age labels, corresponding…

计算机视觉与模式识别 · 计算机科学 2016-06-10 Refik Can Malli , Mehmet Aygun , Hazim Kemal Ekenel

Alzheimer's disease (AD) is the most common age-related dementia. It remains a challenge to identify the individuals at risk of dementia for precise management. Brain MRI offers a noninvasive biomarker to detect brain aging. Previous…

机器学习 · 计算机科学 2021-07-26 Chao Li , Yiran Wei , Xi Chen , Carola-Bibiane Schonlieb

The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

人工智能 · 计算机科学 2021-08-11 Changhyun Park , Heung-Il Suk

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Recent advancements in medicine have confirmed that brain disorders often comprise multiple subtypes of mechanisms, developmental trajectories, or severity levels. Such heterogeneity is often associated with demographic aspects (e.g., sex)…

图像与视频处理 · 电气工程与系统科学 2024-10-08 Magdalini Paschali , Yu Hang Jiang , Spencer Siegel , Camila Gonzalez , Kilian M. Pohl , Akshay Chaudhari , Qingyu Zhao

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…

Demographic attributes such as age, sex, and race can be predicted from medical images, raising concerns about bias in clinical AI systems. In brain MRI, this signal may arise from anatomical variation, acquisition-dependent contrast…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Mehmet Yigit Avci , Akshit Achara , Andrew King , Jorge Cardoso

We are concerned with the challenge of reliably classifying and assessing intracranial aneurysms using deep learning without compromising clinical transparency. While traditional black-box models achieve high predictive accuracy, their lack…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Toqa Khaled , Ahmad Al-Kabbany

The seamless integration of visual and auditory information is a fundamental aspect of human cognition. Although age-related functional changes in Audio-Visual Integration (AVI) have been extensively explored in the past, thorough studies…

信号处理 · 电气工程与系统科学 2023-11-28 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi