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In this study, we proposed and evaluated a graph-based framework to assess variations in Alzheimer's disease (AD) neuropathologies, focusing on classic (cAD) and rapid (rpAD) progression forms. Histopathological images are converted into…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Gabriel Jimenez , Leopold Hebert-Stevens , Benoit Delatour , Lev Stimmer , Daniel Racoceanu

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

机器学习 · 计算机科学 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

神经元与认知 · 定量生物学 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

机器学习 · 计算机科学 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong

The construction of brain graphs from functional Magnetic Resonance Imaging (fMRI) data plays a crucial role in enabling graph machine learning for neuroimaging. However, current practices often rely on rigid pipelines that overlook…

机器学习 · 计算机科学 2025-08-19 Qinwen Ge , Roza G. Bayrak , Anwar Said , Catie Chang , Xenofon Koutsoukos , Tyler Derr

This paper proposes a novel scalable community-based neural framework for graph learning. The framework learns the graph topology through the task of community detection and link prediction by optimizing with our proposed joint SBM loss…

社会与信息网络 · 计算机科学 2020-05-19 Zheng Chen , Xinli Yu , Yuan Ling , Xiaohua Hu

Large scale studies of group differences in healthy controls and patients and screenings for early stage disease prevention programs require processing and analysis of extensive multisubject datasets. Complexity of the task increases even…

计算机视觉与模式识别 · 计算机科学 2017-11-02 Alex Fedorov , Eswar Damaraju , Vince Calhoun , Sergey Plis

Brain network discovery aims to find nodes and edges from the spatio-temporal signals obtained by neuroimaging data, such as fMRI scans of human brains. Existing methods tend to derive representative or average brain networks, assuming…

机器学习 · 计算机科学 2023-11-07 Hang Yin , Yao Su , Xinyue Liu , Thomas Hartvigsen , Yanhua Li , Xiangnan Kong

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

图像与视频处理 · 电气工程与系统科学 2022-02-22 Wessam M. Salama , Ahmed Shokry

Graphs are a powerful tool for representing and analyzing unstructured, non-Euclidean data ubiquitous in the healthcare domain. Two prominent examples are molecule property prediction and brain connectome analysis. Importantly, recent works…

机器学习 · 计算机科学 2022-04-04 Kamilia Mullakaeva , Luca Cosmo , Anees Kazi , Seyed-Ahmad Ahmadi , Nassir Navab , Michael M. Bronstein

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

机器学习 · 计算机科学 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang

In neuroscience, identifying distinct patterns linked to neurological disorders, such as Alzheimer's and Autism, is critical for early diagnosis and effective intervention. Graph Neural Networks (GNNs) have shown promising in analyzing…

机器学习 · 计算机科学 2025-02-05 Jiaxing Xu , Yongqiang Chen , Xia Dong , Mengcheng Lan , Tiancheng Huang , Qingtian Bian , James Cheng , Yiping Ke

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Online health communities such as the online breast cancer forum enable patients (i.e., users) to interact and help each other within various subforums, which are subsections of the main forum devoted to specific health topics. The changing…

机器学习 · 计算机科学 2019-08-23 Yuyang Gao , Lingfei Wu , Houman Homayoun , Liang Zhao

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

机器学习 · 计算机科学 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

人工智能 · 计算机科学 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

机器学习 · 计算机科学 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

机器学习 · 计算机科学 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

Exploiting the relationships between attributes is a key challenge for improving multiple facial attribute recognition. In this work, we are concerned with two types of correlations that are spatial and non-spatial relationships. For the…

计算机视觉与模式识别 · 计算机科学 2021-05-31 Zhenghao Chen , Shuhang Gu , Feng Zhu , Jing Xu , Rui Zhao

Graph theoretical approach has proved an effective tool to understand, characterize and quantify the complex brain network. However, much less attention has been paid to methods that quantitatively compare two graphs, a crucial issue in the…

神经元与认知 · 定量生物学 2019-08-29 Ahmad Mheich , Fabrice Wendling , Mahmoud Hassan