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Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

Large Language Models (LLMs) do not differentially represent numbers, which are pervasive in text. In contrast, neuroscience research has identified distinct neural representations for numbers and words. In this work, we investigate how…

人工智能 · 计算机科学 2024-01-10 Raj Sanjay Shah , Vijay Marupudi , Reba Koenen , Khushi Bhardwaj , Sashank Varma

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

Large Language Models (LLMs) are increasingly used in clinical settings, where sensitivity to linguistic uncertainty can influence diagnostic interpretation and decision-making. Yet little is known about where such epistemic cues are…

计算与语言 · 计算机科学 2025-12-01 Srivarshinee Sridhar , Raghav Kaushik Ravi , Kripabandhu Ghosh

As machine learning models evolve, maintaining transparency demands more human-centric explainable AI techniques. Counterfactual explanations, with roots in human reasoning, identify the minimal input changes needed to obtain a given output…

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang

This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10…

计算与语言 · 计算机科学 2025-07-08 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Large language models (LLM) have achieved impressive performance on medical question-answering benchmarks. However, high benchmark accuracy does not imply that the performance generalizes to real-world clinical settings. Medical…

计算与语言 · 计算机科学 2024-09-04 Robert Osazuwa Ness , Katie Matton , Hayden Helm , Sheng Zhang , Junaid Bajwa , Carey E. Priebe , Eric Horvitz

Clinical robustness is critical to the safe deployment of medical Large Language Models (LLMs), but key questions remain about how LLMs and humans may differ in response to the real-world variability typified by clinical settings. To…

人工智能 · 计算机科学 2025-06-23 Abinitha Gourabathina , Yuexing Hao , Walter Gerych , Marzyeh Ghassemi

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

图像与视频处理 · 电气工程与系统科学 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

The work in this paper evaluates zero-shot and few-shot large language models (LLMs) for safety-critical clinical action extraction using the CLIP discharge-note dataset, with particular emphasis on transitions of care and post-discharge…

人工智能 · 计算机科学 2026-05-08 Shivali Dalmia , Ananya Mantravadi , Prasanna Desikan

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

计算与语言 · 计算机科学 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

计算与语言 · 计算机科学 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

机器学习 · 计算机科学 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Large language models (LLMs) are increasingly embedded in healthcare workflows for documentation, education, and clinical decision support. However, these systems are trained on large text corpora that encode existing biases, including sex…

计算与语言 · 计算机科学 2026-02-05 Isabel Tsintsiper , Sheng Wong , Beth Albert , Shaun P Brennecke , Gabriel Davis Jones

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Multimodal Large Language Models (MLLMs) have shown substantial capabilities in integrating visual and textual information, yet frequently rely on spurious correlations, undermining their robustness and generalization in complex multimodal…

计算与语言 · 计算机科学 2025-09-22 Zichen Wu , Hsiu-Yuan Huang , Yunfang Wu

Large language models (LLMs) show promise in clinical decision support yet risk acquiescing to patient pressure for inappropriate care. We introduce SycoEval-EM, a multi-agent simulation framework evaluating LLM robustness through…

人工智能 · 计算机科学 2026-03-05 Dongshen Peng , Yi Wang , Austin Schoeffler , Carl Preiksaitis , Christian Rose