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Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of…

Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Sheng Wang , Ruiming Wu , Charles Herndon , Yihang Liu , Shunsuke Koga , Jeanne Shen , Zhi Huang

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

计算机视觉与模式识别 · 计算机科学 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness…

图像与视频处理 · 电气工程与系统科学 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Viktoria Ehm , Anke Meyer-Baese , Jan C. Peeken , Daniel Rueckert , Benedikt Wiestler

Multimodal learning, especially large-scale multimodal pre-training, has developed rapidly over the past few years and led to the greatest advances in artificial intelligence (AI). Despite its effectiveness, understanding the underlying…

神经与进化计算 · 计算机科学 2022-08-18 Haoyu Lu , Qiongyi Zhou , Nanyi Fei , Zhiwu Lu , Mingyu Ding , Jingyuan Wen , Changde Du , Xin Zhao , Hao Sun , Huiguang He , Ji-Rong Wen

Intraoperative pathology is pivotal to precision surgery, yet its clinical impact is constrained by diagnostic complexity and the limited availability of high-quality frozen-section data. While computational pathology has made significant…

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Noorul Wahab , Nasir Rajpoot

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Colorectal cancer (CRC) remains the third most prevalent malignancy globally, with approximately 154,000 new cases and 54,000 projected deaths anticipated for 2025. The recent advancement of foundation models in computational pathology has…

计算机视觉与模式识别 · 计算机科学 2025-10-17 Usama Sajjad , Abdul Rehman Akbar , Ziyu Su , Deborah Knight , Wendy L. Frankel , Metin N. Gurcan , Wei Chen , Muhammad Khalid Khan Niazi

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Multiple instance learning (MIL)-based framework has become the mainstream for processing the whole slide image (WSI) with giga-pixel size and hierarchical image context in digital pathology. However, these methods heavily depend on a…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Jiangbo Shi , Chen Li , Tieliang Gong , Yefeng Zheng , Huazhu Fu

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

Foundation vision encoders such as CLIP and DINOv2, trained on web-scale data, exhibit strong transfer performance across tasks and datasets. However, medical imaging foundation models remain constrained by smaller datasets, limiting our…

Foundation models (FM) have transformed computational pathology but remain computationally prohibitive for clinical deployment due to their massive parameter counts and high-magnification processing requirements. Here, we introduce XMAG, a…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Anil V. Parwani , Muhammad Khalid Khan Niazi

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Multimodal large language models (MLLMs) have achieved remarkable progress on vision-language tasks, yet their reasoning processes remain sometimes unreliable. We introduce PRISM-Bench, a benchmark of puzzle-based visual challenges designed…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Yusu Qian , Cheng Wan , Chao Jia , Yinfei Yang , Qingyu Zhao , Zhe Gan

Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…

计算机视觉与模式识别 · 计算机科学 2024-07-30 Honglin Li , Yusuan Sun , Chenglu Zhu , Yunlong Zhang , Shichuan Zhang , Zhongyi Shui , Pingyi Chen , Jingxiong Li , Sunyi Zheng , Can Cui , Lin Yang

Recently, histopathology vision-language foundation models (VLMs) have gained popularity due to their enhanced performance and generalizability across different downstream tasks. However, most existing histopathology benchmarks are either…

图像与视频处理 · 电气工程与系统科学 2025-03-18 Roba Al Majzoub , Hashmat Malik , Muzammal Naseer , Zaigham Zaheer , Tariq Mahmood , Salman Khan , Fahad Khan