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The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…

Foundation models are increasingly developed in computational pathology (CPath) given their promise in facilitating many downstream tasks. While recent studies have evaluated task performance across models, less is known about the structure…

计算机视觉与模式识别 · 计算机科学 2025-11-07 Vaibhav Mishra , William Lotter

The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

Histopathology is essential for disease diagnosis and treatment decision-making. Recent advances in artificial intelligence (AI) have enabled the development of pathology foundation models that learn rich visual representations from…

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

计算机视觉与模式识别 · 计算机科学 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Advancements in artificial intelligence have driven the development of numerous pathology foundation models capable of extracting clinically relevant information. However, there is currently limited literature independently evaluating these…

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen…

图像与视频处理 · 电气工程与系统科学 2024-09-05 Mingya Zhang , Liang Wang , Zhihao Chen , Yiyuan Ge , Xianping Tao

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However,…

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts…

图像与视频处理 · 电气工程与系统科学 2024-08-21 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…