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Deep neural network models can learn clinically relevant features from millions of histopathology images. However generating high-quality annotations to train such models for each hospital, each cancer type, and each diagnostic task is…

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

计算机视觉与模式识别 · 计算机科学 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

机器学习 · 计算机科学 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

图像与视频处理 · 电气工程与系统科学 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Uncertainty estimation is important for interpreting the trustworthiness of machine learning models in many applications. This is especially critical in the data-driven active learning setting where the goal is to achieve a certain accuracy…

计算机视觉与模式识别 · 计算机科学 2020-07-14 Bo Li , Tommy Sonne Alstrøm

Breast cancer is a heterogeneous disease with different molecular subtypes, clinical behavior, treatment responses as well as survival outcomes. The development of a reliable, accurate, available and inexpensive method to predict the…

计算机视觉与模式识别 · 计算机科学 2024-12-20 Mohaddeseh Chegini , Ali Mahloojifar

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

计算机视觉与模式识别 · 计算机科学 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…

图像与视频处理 · 电气工程与系统科学 2021-07-27 Donya Khaledyan , AmirReza Tajally , Ali Sarkhosh , Afshar Shamsi , Hamzeh Asgharnezhad , Abbas Khosravi , Saeid Nahavandi

Cancer is one of the deadliest diseases worldwide. Accurate diagnosis and classification of cancer subtypes are indispensable for effective clinical treatment. Promising results on automatic cancer subtyping systems have been published…

机器学习 · 计算机科学 2022-04-06 Ziwei Yang , Lingwei Zhu , Zheng Chen , Ming Huang , Naoaki Ono , MD Altaf-Ul-Amin , Shigehiko Kanaya

The problem of fully supervised classification is that it requires a tremendous amount of annotated data, however, in many datasets a large portion of data is unlabeled. To alleviate this problem semi-supervised learning (SSL) leverages the…

机器学习 · 计算机科学 2022-07-26 Ehsan Kazemi

Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

Prediction of survival for cancer patients is an open area of research. However, many of these studies focus on datasets with a large number of patients. We present a novel method that is specifically designed to address the challenge of…

机器学习 · 计算机科学 2015-09-30 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

计算机视觉与模式识别 · 计算机科学 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

计算机视觉与模式识别 · 计算机科学 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

State-of-the-art machine learning models require access to significant amount of annotated data in order to achieve the desired level of performance. While unlabelled data can be largely available and even abundant, annotation process can…

机器学习 · 计算机科学 2020-10-15 Rahaf Aljundi , Nikolay Chumerin , Daniel Olmeda Reino

Deep Learning sets the state-of-the-art in many challenging tasks showing outstanding performance in a broad range of applications. Despite its success, it still lacks robustness hindering its adoption in medical applications. Modeling…

计算机视觉与模式识别 · 计算机科学 2019-09-19 Agnieszka Tomczack , Nassir Navab , Shadi Albarqouni

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

图像与视频处理 · 电气工程与系统科学 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker

Uncertainty estimation is at the core of Active Learning (AL). Most existing methods resort to complex auxiliary models and advanced training fashions to estimate uncertainty for unlabeled data. These models need special design and hence…

计算机视觉与模式识别 · 计算机科学 2025-09-22 Tianyang Wang , Xi Xiao , Gaofei Chen , Xiaoying Liao , Guo Cheng , Yingrui Ji
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