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In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the…

计算与语言 · 计算机科学 2025-08-06 Penglei Sun , Yixiang Chen , Xiang Li , Xiaowen Chu

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

计算与语言 · 计算机科学 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

计算与语言 · 计算机科学 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

计算与语言 · 计算机科学 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

计算与语言 · 计算机科学 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

计算与语言 · 计算机科学 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

计算机视觉与模式识别 · 计算机科学 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

计算与语言 · 计算机科学 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

计算与语言 · 计算机科学 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Accurate and reliable search on online healthcare platforms is critical for user safety and service efficacy. Traditional methods, however, often fail to comprehend complex and nuanced user queries, limiting their effectiveness. Large…

计算与语言 · 计算机科学 2025-12-04 Chuyue Wang , Jie Feng , Yuxi Wu , Hang Zhang , Zhiguo Fan , Bing Cheng , Wei Lin

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

计算与语言 · 计算机科学 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

定量方法 · 定量生物学 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

计算与语言 · 计算机科学 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

计算与语言 · 计算机科学 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

计算与语言 · 计算机科学 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

计算与语言 · 计算机科学 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Large language models (LLMs) and large multimodal models (LMMs) promise to accelerate biomedical discovery, yet their reliability remains unclear. We introduce ARIEL (AI Research Assistant for Expert-in-the-Loop Learning), an open-source…

Large Language Models (LLMs) have shown impressive potential in clinical question answering (QA), with Retrieval Augmented Generation (RAG) emerging as a leading approach for ensuring the factual accuracy of model responses. However,…

计算与语言 · 计算机科学 2025-07-21 Mohita Chowdhury , Yajie Vera He , Jared Joselowitz , Aisling Higham , Ernest Lim
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