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Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

图像与视频处理 · 电气工程与系统科学 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

图像与视频处理 · 电气工程与系统科学 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Self-supervised learning (SSL) has emerged as a promising paradigm for addressing the annotation bottleneck in medical imaging by learning representations from unlabeled data. However, its effectiveness depends heavily on the design of the…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Chathura Wimalasiri

Whole slide image (WSI) has been widely used to assist automated diagnosis under the deep learning fields. However, most previous works only discuss the SINGLE task setting which is not aligned with real clinical setting, where pathologists…

计算机视觉与模式识别 · 计算机科学 2023-03-31 Weiqin Zhao , Shujun Wang , Maximus Yeung , Tianye Niu , Lequan Yu

While Whole Slide Imaging (WSI) scanners remain the gold standard for digitizing pathology samples, their high cost limits accessibility in many healthcare settings. Other low-cost solutions also face critical limitations: automated…

计算机视觉与模式识别 · 计算机科学 2025-10-08 Yousef Yeganeh , Maximilian Frantzen , Michael Lee , Kun-Hsing Yu , Nassir Navab , Azade Farshad

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Multiple Instance Learning (MIL), a powerful strategy for weakly supervised learning, is able to perform various prediction tasks on gigapixel Whole Slide Images (WSIs). However, the tens of thousands of patches in WSIs usually incur a vast…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Zhuchen Shao , Liuxi Dai , Yifeng Wang , Haoqian Wang , Yongbing Zhang

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini

Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

计算机视觉与模式识别 · 计算机科学 2025-07-25 Bryan Wong , Mun Yong Yi

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

计算机视觉与模式识别 · 计算机科学 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

Few-shot semantic segmentation (FSS) is a crucial challenge in computer vision, driving extensive research into a diverse range of methods, from advanced meta-learning techniques to simple transfer learning baselines. With the emergence of…

计算机视觉与模式识别 · 计算机科学 2025-06-04 Reda Bensaid , Vincent Gripon , François Leduc-Primeau , Lukas Mauch , Ghouthi Boukli Hacene , Fabien Cardinaux

The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain MRI alone. Human aging and disease arise through coordinated biological processes across…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Qiangqiang Wu , Grace McIlvain , Zhou Yu , Junhao Wen
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