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Self-generated gradients have atttracted a lot of attention in the recent biological literature. It is considered as a robust strategy for a group of cells to find its way during a long journey. This note is intended to discuss various…

偏微分方程分析 · 数学 2021-09-15 Mete Demircigil , Vincent Calvez , Roxana Sublet

Chemotaxis in bacteria such as \textit{E.\ coli} is controlled by the slow methylation of chemoreceptors. As a consequence, intrinsic time and length scales of tens of seconds and hundreds of micrometers emerge, making the Keller--Segel…

软凝聚态物质 · 物理学 2025-04-23 Manuel Mayo , Rodrigo Soto

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

种群与进化 · 定量生物学 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

In bacterial chemotaxis, E. coli cells drift up chemical gradients by a series of runs and tumbles. Runs are periods of directed swimming, and tumbles are abrupt changes in swimming direction. Near the beginning of each run, the rotating…

软凝聚态物质 · 物理学 2009-11-07 Thomas R. Powers

Bacteria are often exposed to multiple stimuli in complex environments, and their efficient chemotactic decisions are critical to survive and grow in their native environments. Bacterial responses to the environmental stimuli depend on the…

定量方法 · 定量生物学 2021-06-10 Jeungeun Park , Zahra Aminzare

Many chemotactic bacteria inhabit environments in which chemicals appear as localized pulses and evolve by processes such as diffusion and mixing. We show that, in such environments, physical limits on the accuracy of temporal gradient…

生物物理 · 物理学 2016-01-19 Andrew M. Hein , Douglas R. Brumley , Francesco Carrara , Roman Stocker , Simon A. Levin

Near a solid boundary, E. coli swims in clockwise circular motion. We provide a hydrodynamic model for this behavior. We show that circular trajectories are natural consequences of force-free and torque-free swimming, and the hydrodynamic…

软凝聚态物质 · 物理学 2016-08-31 Eric Lauga , Willow R. DiLuzio , George M. Whitesides , Howard A. Stone

Chemotactic cells establish cell polarity in the absence of external guidance cues. Such self-organized polarity is induced by spontaneous symmetry breaking in the intracellular activities, which produces an emergent memory effect…

细胞行为 · 定量生物学 2015-06-16 Tetsuya Hiraiwa , Akihiro Nagamatsu , Naohiro Akuzawa , Masatoshi Nishikawa , Tatsuo Shibata

We use moving light patterns to control the motion of {\it Escherichia coli} bacteria whose motility is photo-activated. Varying the pattern speed controls the magnitude and direction of the bacterial flux, and therefore the accumulation of…

Cells are constantly exposed to diverse stimuli-chemical, mechanical, or electrical-that guide their movement. In physiological conditions, these signals often overlap, as seen during infections, where neutrophils and dendritic cells…

生物物理 · 物理学 2026-03-25 Emiliano Perez Ipiña , Brian A. Camley

Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an…

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

分子网络 · 定量生物学 2019-08-19 Thierry Emonet , Philippe Cluzel

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

统计力学 · 物理学 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

生物物理 · 物理学 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

An interacting pair of chemotactic (anti-chemotactic) active colloids, that can rotate their axes of self-propulsion to align {parallel (anti-parallel)} to a chemical gradient, shows dynamical behaviour that varies from bound states to…

生物物理 · 物理学 2025-10-08 Suropriya Saha , Sriram Ramaswamy , Ramin Golestanian

Living microorganisms are capable of a tactic response to external stimuli by swimming towards or away from the stimulus source; they do so by adapting their tactic signal transduction pathways to the environment. Their self-motility thus…

软凝聚态物质 · 物理学 2016-10-12 Alexander Geiseler , Peter Hänggi , Fabio Marchesoni , Colm Mulhern , Sergey Savel'ev

In the chemotactic motion of Escherichia coli, the switching of transmembrane chemoreceptors between active and inactive states is one of the most important steps of the signaling pathway. We study the effect of this switching time-scale on…

细胞行为 · 定量生物学 2022-08-18 Shobhan Dev Mandal , Sakuntala Chatterjee

Living cells are capable of interacting with their environments in a variety of ways, including cell signalling, adhesion, and directed motion. These behaviours are often mediated by receptor molecules embedded in the cell membrane, which…

生物物理 · 物理学 2023-10-17 Hannah Sleath , Bortolo Mognetti , Yuval Elani , Lorenzo Di Michele

Active navigation in disordered media depends on a biased random walk interacting with environmental constraints. Using E. coli chemotactic navigation in agar gels as a model system, we reveal a fundamental trade-off between diffusive…

软凝聚态物质 · 物理学 2025-12-23 Yang Bai , Caiyun He , Weirong Liu , Songtao Cheng , Pan Chu , Liang Luo , Chenli Liu , Xiongfei Fu

We numerically investigate the motion of active artificial microswimmers diffusing in a fuel concentration gradient. We observe that, in the steady state, their probability density accumulates in the low-concentration regions, whereas a…

软凝聚态物质 · 物理学 2025-08-18 Pulak K. Ghosh , Yunyun Li , Fabio Marchesoni , Franco Nori