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相关论文: Deep Learning for Retinal Degeneration Assessment:…

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Neovascular age-related macular degeneration (nAMD) is a leading cause of vision loss among older adults, where disease activity detection and progression prediction are critical for nAMD management in terms of timely drug administration…

图像与视频处理 · 电气工程与系统科学 2025-01-27 Taha Emre , Teresa Araújo , Marzieh Oghbaie , Dmitrii Lachinov , Guilherme Aresta , Hrvoje Bogunović

By 2040, age-related macular degeneration (AMD) will affect approximately 288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the sight-threatening stage, is critical for clinical actions,…

图像与视频处理 · 电气工程与系统科学 2020-07-21 Yifan Peng , Tiarnan D. Keenan , Qingyu Chen , Elvira Agrón , Alexis Allot , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Age-related Macular Degeneration (AMD) is a prevalent eye condition affecting visual acuity. Anti-vascular endothelial growth factor (anti-VEGF) treatments have been effective in slowing the progression of neovascular AMD, with better…

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

机器学习 · 计算机科学 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Background: Patients with neovascular age-related macular degeneration (AMD) can avoid vision loss via certain therapy. However, methods to predict the progression to neovascular age-related macular degeneration (nvAMD) are lacking.…

计算机视觉与模式识别 · 计算机科学 2019-04-12 Boris Babenko , Siva Balasubramanian , Katy E. Blumer , Greg S. Corrado , Lily Peng , Dale R. Webster , Naama Hammel , Avinash V. Varadarajan

We propose a hybrid sequential deep learning model to predict the risk of AMD progression in non-exudative AMD eyes at multiple timepoints, starting from short-term progression (3-months) up to long-term progression (21-months). Proposed…

定量方法 · 定量生物学 2019-03-01 Imon Banerjee , Luis de Sisternes , Joelle Hallak , Theodore Leng , Aaron Osborne , Mary Durbin , Daniel Rubin

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

机器学习 · 统计学 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

Today, more than 12 million people over the age of 40 suffer from ocular diseases. Most commonly, older patients are susceptible to age related macular degeneration, an eye disease that causes blurring of the central vision due to the…

图像与视频处理 · 电气工程与系统科学 2022-05-03 Ananya Dua , Pham Hung Minh , Sajid Fahmid , Shikhar Gupta , Sophia Zheng , Vanessa Moyo , Yanran Elisa Xue

Despite strong performance of deep learning models in retinal disease detection, most systems produce static predictions without clinical reasoning or interactive explanation. Recent advances in multimodal large language models (MLLMs)…

计算机视觉与模式识别 · 计算机科学 2026-04-29 Ran Gu , Benjamin Hou , Mélanie Hébert , Asmita Indurkar , Yifan Yang , Emily Y. Chew , Tiarnán D. L. Keenan , Zhiyong Lu

Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…

基因组学 · 定量生物学 2024-09-10 Kuan Yan , Yue Zeng , Dai Shi , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

This work aims to research an automatic method for detecting Age-related Macular Degeneration (AMD) lesions in RGB eye fundus images. For this, we align invasively obtained eye fundus contrast images (the "golden standard" diagnostic) to…

图像与视频处理 · 电气工程与系统科学 2021-10-19 Rokas Pečiulis , Mantas Lukoševičius , Algimantas Kriščiukaitis , Robertas Petrolis , Dovilė Buteikienė

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Machine Learning (ML) is used to tackle various tasks, such as disease classification and prediction. The effectiveness of ML models relies heavily on having large amounts of complete data. However, healthcare data is often limited or…

In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

计算机视觉与模式识别 · 计算机科学 2019-01-29 Yifan Peng , Shazia Dharssi , Qingyu Chen , Tiarnan D. Keenan , Elvira Agrón , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

We propose a method to predict severity of age related macular degeneration (AMD) from input optical coherence tomography (OCT) images. Although there is no standard clinical severity scale for AMD, we leverage deep learning (DL) based…

计算机视觉与模式识别 · 计算机科学 2019-07-09 Dwarikanath Mahapatra
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