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Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

人机交互 · 计算机科学 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

There is a lack of benchmarks for evaluating large language models (LLMs) in long-form medical question answering (QA). Most existing medical QA evaluation benchmarks focus on automatic metrics and multiple-choice questions. While valuable,…

计算与语言 · 计算机科学 2024-11-21 Pedram Hosseini , Jessica M. Sin , Bing Ren , Bryceton G. Thomas , Elnaz Nouri , Ali Farahanchi , Saeed Hassanpour

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

计算与语言 · 计算机科学 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

计算与语言 · 计算机科学 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

计算与语言 · 计算机科学 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

计算与语言 · 计算机科学 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

计算与语言 · 计算机科学 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

计算与语言 · 计算机科学 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

计算与语言 · 计算机科学 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

The wide exploration of large language models (LLMs) raises the awareness of alignment between healthcare stakeholder preferences and model outputs. This alignment becomes a crucial foundation to empower the healthcare workflow effectively,…

计算机与社会 · 计算机科学 2025-05-07 Kexin Ding , Mu Zhou , Akshay Chaudhari , Shaoting Zhang , Dimitris N. Metaxas

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Patients are increasingly turning to large language models (LLMs) with medical questions that are complex and difficult to articulate clearly. However, LLMs are sensitive to prompt phrasings and can be influenced by the way questions are…

计算与语言 · 计算机科学 2026-04-08 Hye Sun Yun , Geetika Kapoor , Michael Mackert , Ramez Kouzy , Wei Xu , Junyi Jessy Li , Byron C. Wallace

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

计算机与社会 · 计算机科学 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla
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