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相关论文: BioReason: Incentivizing Multimodal Biological Rea…

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Large language models (LLMs) have shown impressive promise in code generation, yet their progress remains limited by the shortage of large-scale datasets that are both diverse and well-aligned with human reasoning. Most existing resources…

机器学习 · 计算机科学 2025-10-28 Amal Abed , Ivan Lukic , Jörg K. H. Franke , Frank Hutter

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

计算与语言 · 计算机科学 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

High-content perturbation experiments allow scientists to probe biomolecular systems at unprecedented resolution, but experimental and analysis costs pose significant barriers to widespread adoption. Machine learning has the potential to…

Multimodal Large Language Models (LLMs) hold promise for biomedical reasoning, but current benchmarks fail to capture the complexity of real-world clinical workflows. Existing evaluations primarily assess unimodal, decontextualized…

Although DNA foundation models have advanced the understanding of genomes, they still face significant challenges in the limited scale and diversity of genomic data. This limitation starkly contrasts with the success of natural language…

基因组学 · 定量生物学 2024-02-14 Huixin Zhan , Ying Nian Wu , Zijun Zhang

Large language models (LLMs) have achieved remarkable progress in solving various natural language processing tasks due to emergent reasoning abilities. However, LLMs have inherent limitations as they are incapable of accessing up-to-date…

计算与语言 · 计算机科学 2023-11-01 Pan Lu , Baolin Peng , Hao Cheng , Michel Galley , Kai-Wei Chang , Ying Nian Wu , Song-Chun Zhu , Jianfeng Gao

Logical reasoning is a pivotal component in the field of artificial intelligence. Proof planning, particularly in contexts requiring the validation of explanation accuracy, continues to present challenges. The recent advancement of large…

计算与语言 · 计算机科学 2025-10-31 Ying Su , Mingwen Liu , Zhijiang Guo

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

计算与语言 · 计算机科学 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Retrosynthesis planning, essential in organic synthesis and drug discovery, has greatly benefited from recent AI-driven advancements. Nevertheless, existing methods frequently face limitations in both applicability and explainability.…

计算工程、金融与科学 · 计算机科学 2025-07-24 Situo Zhang , Hanqi Li , Lu Chen , Zihan Zhao , Xuanze Lin , Zichen Zhu , Bo Chen , Xin Chen , Kai Yu

We propose Neural Reasoner, a framework for neural network-based reasoning over natural language sentences. Given a question, Neural Reasoner can infer over multiple supporting facts and find an answer to the question in specific forms.…

人工智能 · 计算机科学 2015-08-25 Baolin Peng , Zhengdong Lu , Hang Li , Kam-Fai Wong

Recent advances in Multi-Modal Large Language Models (MLLMs) have enabled unified processing of language, vision, and structured inputs, opening the door to complex tasks such as logical deduction, spatial reasoning, and scientific…

人工智能 · 计算机科学 2025-07-03 Guiyao Tie , Xueyang Zhou , Tianhe Gu , Ruihang Zhang , Chaoran Hu , Sizhe Zhang , Mengqu Sun , Yan Zhang , Pan Zhou , Lichao Sun

Large Language Models (LLMs) have achieved remarkable success in natural language tasks, yet understanding their reasoning processes remains a significant challenge. We address this by introducing XplainLLM, a dataset accompanying an…

计算与语言 · 计算机科学 2024-09-24 Zichen Chen , Jianda Chen , Ambuj Singh , Misha Sra

Large Language Models (LLMs) have unveiled remarkable capabilities in understanding and generating both natural language and code, but LLM reasoning is prone to hallucination and struggle with complex, novel scenarios, often getting stuck…

神经与进化计算 · 计算机科学 2025-05-12 Antonio Jimeno Yepes , Pieter Barnard

Modeling biological sequences such as DNA, RNA, and proteins is crucial for understanding complex processes like gene regulation and protein synthesis. However, most current models either focus on a single type or treat multiple types of…

基因组学 · 定量生物学 2024-10-16 Weixi Xiang , Xueting Han , Xiujuan Chai , Jing Bai

With the increasing use of large language models (LLMs) for generating answers to biomedical questions, it is crucial to evaluate the quality of the generated answers and the references provided to support the facts in the generated…

计算与语言 · 计算机科学 2026-02-10 Deepak Gupta , Davis Bartels , Dina Demner-Fushman

Large language models (LLMs) solve complex problems yet fail on simpler variants, suggesting they achieve correct outputs through mechanisms fundamentally different from human reasoning. To understand this gap, we synthesize cognitive…

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

Artificial Intelligence (AI) models increasingly drive high-stakes consumer interactions, yet their decision logic often remains opaque. Prevailing explainable AI techniques rely on post hoc numerical feature attributions, which fail to…

计算与语言 · 计算机科学 2026-01-09 Xiang Cheng , Wen Wang , Anindya Ghose

Reasoning has substantially improved the performance of large language models (LLMs) on complicated tasks. Central to the current reasoning studies, Process Reward Models (PRMs) offer a fine-grained evaluation of intermediate reasoning…

机器学习 · 计算机科学 2025-11-05 Qi Cao , Ruiyi Wang , Ruiyi Zhang , Sai Ashish Somayajula , Pengtao Xie

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

计算机视觉与模式识别 · 计算机科学 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li