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The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

计算与语言 · 计算机科学 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Drug discovery (DD) has tremendously contributed to maintaining and improving public health. Hypothesizing that inhibiting protein misfolding can slow disease progression, researchers focus on target identification (Target ID) to find…

定量方法 · 定量生物学 2025-01-29 Ziwen Li , Xiang 'Anthony' Chen , Youngseung Jeon

As healthcare increasingly turns to AI for scalable and trustworthy clinical decision support, ensuring reliability in model reasoning remains a critical challenge. Individual large language models (LLMs) are susceptible to hallucinations…

机器学习 · 计算机科学 2025-12-05 Huascar Sanchez , Briland Hitaj , Jules Bergmann , Linda Briesemeister

Clinical practice guidelines (CPGs) play a pivotal role in ensuring evidence-based decision-making and improving patient outcomes. While Large Language Models (LLMs) are increasingly deployed in healthcare scenarios, it is unclear to which…

计算与语言 · 计算机科学 2026-03-27 Andong Tan , Shuyu Dai , Jinglu Wang , Fengtao Zhou , Yan Lu , Xi Wang , Yingcong Chen , Can Yang , Shujie Liu , Hao Chen

In high-stakes information domains such as healthcare, where large language models (LLMs) can produce hallucinations or misinformation, retrieval-augmented generation (RAG) has been proposed as a mitigation strategy, grounding model outputs…

信息检索 · 计算机科学 2026-04-07 Saeedeh Javadi , Sara Mirabi , Manan Gangar , Bahadorreza Ofoghi

Large Language Models (LLMs) have demonstrated remarkable capabilities in modeling sequential textual data and generalizing across diverse tasks. However, adapting LLMs to effectively handle structural data, such as knowledge graphs or web…

计算与语言 · 计算机科学 2025-11-12 Jiarui Feng , Donghong Cai , Yixin Chen , Muhan Zhang

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

人工智能 · 计算机科学 2025-09-16 Susanta Mitra

Therapy recommendation for chronic patients with multimorbidity is challenging due to risks of treatment conflicts. Existing decision support systems face scalability limitations. Inspired by the way in which general practitioners (GP)…

人工智能 · 计算机科学 2025-07-16 Yicong Wu , Ting Chen , Irit Hochberg , Zhoujian Sun , Ruth Edry , Zhengxing Huang , Mor Peleg

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

计算与语言 · 计算机科学 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

计算与语言 · 计算机科学 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

E-learning environments are increasingly harnessing large language models (LLMs) like GPT-3.5 and GPT-4 for tailored educational support. This study introduces an approach that integrates dynamic knowledge graphs with LLMs to offer nuanced…

人工智能 · 计算机科学 2024-12-06 Patrick Ocheja , Brendan Flanagan , Yiling Dai , Hiroaki Ogata

This paper proposes a graph-augmented reasoning framework for tobacco pest and disease management that integrates structured domain knowledge into large language models. Building on GraphRAG, we construct a domain-specific knowledge graph…

计算与语言 · 计算机科学 2026-02-04 Siyu Li , Chenwei Song , Qi Zhou , Wan Zhou , Xinyi Liu

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

计算与语言 · 计算机科学 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Large Language Models (LLMs) often struggle with inherent knowledge boundaries and hallucinations, limiting their reliability in knowledge-intensive tasks. While Retrieval-Augmented Generation (RAG) mitigates these issues, it frequently…

人工智能 · 计算机科学 2026-02-25 Yuqi Huang , Ning Liao , Kai Yang , Anning Hu , Shengchao Hu , Xiaoxing Wang , Junchi Yan

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

人工智能 · 计算机科学 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

信息检索 · 计算机科学 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Conversational Recommender Systems (CRSs) aim to provide personalized recommendations by capturing user preferences through interactive dialogues. Explainability in CRSs is crucial as it enables users to understand the reasoning behind…

计算与语言 · 计算机科学 2025-10-03 Zhangchi Qiu , Linhao Luo , Shirui Pan , Alan Wee-Chung Liew

Large Language Models (LLMs) have shown strong potential in recommender systems due to their contextual learning and generalisation capabilities. Existing LLM-based recommendation approaches typically formulate the recommendation task using…

信息检索 · 计算机科学 2025-07-09 Zeyuan Meng , Zixuan Yi , Iadh Ounis

This study investigates the feasibility of developing an Artificial General Recommender (AGR), facilitated by recent advancements in Large Language Models (LLMs). An AGR comprises both conversationality and universality to engage in natural…

信息检索 · 计算机科学 2023-05-09 Guo Lin , Yongfeng Zhang

Large language models (LLMs) exhibit strong semantic understanding, yet struggle when user instructions involve ambiguous or conceptually misaligned terms. We propose the Language Graph Model (LGM) to enhance conceptual clarity by…

计算与语言 · 计算机科学 2025-11-06 Wenchang Lei , Ping Zou , Yue Wang , Feng Sun , Lei Zhao