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相关论文: Disentangling Reasoning and Knowledge in Medical L…

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Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

计算与语言 · 计算机科学 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

计算与语言 · 计算机科学 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

This study evaluates causal reasoning in large language models (LLMs) using 99 clinically grounded laboratory test scenarios aligned with Pearl's Ladder of Causation: association, intervention, and counterfactual reasoning. We examined…

人工智能 · 计算机科学 2025-09-23 Balu Bhasuran , Mattia Prosperi , Karim Hanna , John Petrilli , Caretia JeLayne Washington , Zhe He

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

计算与语言 · 计算机科学 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

计算与语言 · 计算机科学 2025-09-16 Can Wang , Yiqun Chen

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Large language models are often assumed to acquire increasingly structured, generalizable internal representations simply by scaling data and parameters. We interrogate this assumption by introducing a Clinical Trial Natural Language…

人工智能 · 计算机科学 2025-08-15 Maël Jullien , Marco Valentino , André Freitas

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

计算与语言 · 计算机科学 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

计算与语言 · 计算机科学 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu

While Large Language Models (LLMs) achieve expert-level performance on standard medical benchmarks through single-hop factual recall, they severely struggle with the complex, multi-hop diagnostic reasoning required in real-world clinical…

计算与语言 · 计算机科学 2026-03-16 Xing Zi , Xinying Zhou , Jinghao Xiao , Catarina Moreira , Mukesh Prasad

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

人工智能 · 计算机科学 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

While large language models (LLMs) have demonstrated impressive capabilities across various natural language processing tasks by acquiring rich factual knowledge from their broad training data, their ability to synthesize and logically…

计算与语言 · 计算机科学 2024-07-31 Tianshi Zheng , Jiaxin Bai , Yicheng Wang , Tianqing Fang , Yue Guo , Yauwai Yim , Yangqiu Song

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though…

计算与语言 · 计算机科学 2024-12-30 Junying Chen , Zhenyang Cai , Ke Ji , Xidong Wang , Wanlong Liu , Rongsheng Wang , Jianye Hou , Benyou Wang

Large language models (LLMs) have shown remarkable improvements in reasoning and many existing benchmarks have been addressed by models such as o1 and o3 either fully or partially. However, a majority of these benchmarks emphasize deductive…

机器学习 · 计算机科学 2025-05-15 Wenyue Hua , Tyler Wong , Sun Fei , Liangming Pan , Adam Jardine , William Yang Wang

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

计算与语言 · 计算机科学 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

计算与语言 · 计算机科学 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited…

计算与语言 · 计算机科学 2025-01-14 Haochun Wang , Sendong Zhao , Zewen Qiang , Zijian Li , Nuwa Xi , Yanrui Du , MuZhen Cai , Haoqiang Guo , Yuhan Chen , Haoming Xu , Bing Qin , Ting Liu

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

计算与语言 · 计算机科学 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman