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Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities across diverse tasks, yet they lag significantly behind humans in spatial reasoning. We investigate this gap through Transformation-Driven Visual Reasoning…

计算机视觉与模式识别 · 计算机科学 2025-07-11 Zongzhao Li , Zongyang Ma , Mingze Li , Songyou Li , Yu Rong , Tingyang Xu , Ziqi Zhang , Deli Zhao , Wenbing Huang

Multimodal Large Language Models (MLLMs) are making significant progress in multimodal reasoning. Early approaches focus on pure text-based reasoning. More recent studies have incorporated multimodal information into the reasoning steps;…

人工智能 · 计算机科学 2026-04-21 Dongjie Cheng , Yongqi Li , Zhixin Ma , Hongru Cai , Yupeng Hu , Wenjie Wang , Liqiang Nie , Wenjie Li

Deep learning in \emph{de novo} protein design has achieved atomic-level fidelity. However, existing models remain largely non-deliberative: they directly synthesize molecular geometries without explicitly reasoning about which residues or…

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains.…

人工智能 · 计算机科学 2025-05-27 Shaohao Rui , Kaitao Chen , Weijie Ma , Xiaosong Wang

When thinking with images, humans rarely rely on a single glance: they revisit visual evidence while reasoning. In contrast, most Multimodal Language Models encode an image once to key-value cache and then reason purely in text, making it…

计算与语言 · 计算机科学 2026-05-08 Jiwan Chung , Junhyeok Kim , Siyeol Kim , Jaeyoung Lee , Min Soo Kim , Youngjae Yu

Despite recent advancements in Multi-modal Large Language Models (MLLMs) on diverse understanding tasks, these models struggle to solve problems which require extensive multi-step reasoning. This is primarily due to the progressive dilution…

计算机视觉与模式识别 · 计算机科学 2026-05-13 Byungwoo Jeon , Yoonwoo Jeong , Hyunseok Lee , Minsu Cho , Jinwoo Shin

Vision language models (VLMs) achieve strong performance on general image understanding but struggle to think with medical images, especially when performing multi-step reasoning through iterative visual interaction. Medical VLMs often rely…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Meng Lu , Yuxing Lu , Yuchen Zhuang , Megan Mullins , Yang Xie , Guanghua Xiao , Charles Fleming , Wenqi Shi , Xuan Wang

Large Multimodal Models (LMMs) demonstrate significant cross-modal reasoning capabilities. However, financial applications face challenges due to the lack of high-quality multimodal reasoning datasets and the inefficiency of existing…

计算与语言 · 计算机科学 2025-06-17 Kai Lan , Jiayong Zhu , Jiangtong Li , Dawei Cheng , Guang Chen , Changjun Jiang

While recent advancements in reasoning optimization have significantly enhanced the capabilities of large language models (LLMs), existing efforts to improve reasoning have been limited to solving mathematical problems and focusing on…

计算机视觉与模式识别 · 计算机科学 2025-02-18 Guangzhi Sun , Yudong Yang , Jimin Zhuang , Changli Tang , Yixuan Li , Wei Li , Zejun MA , Chao Zhang

Current large vision-language models (LVLMs) typically employ a connector module to link visual features with text embeddings of large language models (LLMs) and use end-to-end training to achieve multi-modal understanding in a unified…

人工智能 · 计算机科学 2025-08-14 Zixian Guo , Ming Liu , Qilong Wang , Zhilong Ji , Jinfeng Bai , Lei Zhang , Wangmeng Zuo

Amidst a shortage of qualified mental health professionals, the integration of large language models (LLMs) into psychological applications offers a promising way to alleviate the growing burden of mental health disorders. Recent…

计算与语言 · 计算机科学 2025-08-25 Chongyuan Dai , Jinpeng Hu , Hongchang Shi , Zhuo Li , Xun Yang , Meng Wang

Vision-language models in pathology enable multimodal case retrieval and automated report generation. Many of the models developed so far, however, have been trained on pathology reports that include information which cannot be inferred…

计算机视觉与模式识别 · 计算机科学 2025-06-09 Ruben T. Lucassen , Tijn van de Luijtgaarden , Sander P. J. Moonemans , Gerben E. Breimer , Willeke A. M. Blokx , Mitko Veta

While large multimodal models (LMMs) have demonstrated strong performance across various Visual Question Answering (VQA) tasks, certain challenges require complex multi-step reasoning to reach accurate answers. One particularly challenging…

In this paper, we consider the problem of visual representation learning for computational pathology, by exploiting large-scale image-text pairs gathered from public resources, along with the domain-specific knowledge in pathology.…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Xiao Zhou , Xiaoman Zhang , Chaoyi Wu , Ya Zhang , Weidi Xie , Yanfeng Wang

Accurately grounding regions of interest (ROIs) is critical for diagnosis and treatment planning in medical imaging. While multimodal large language models (MLLMs) combine visual perception with natural language, current medical-grounding…

计算机视觉与模式识别 · 计算机科学 2026-02-19 Zhonghao Yan , Muxi Diao , Yuxuan Yang , Ruoyan Jing , Jiayuan Xu , Kaizhou Zhang , Lele Yang , Yanxi Liu , Kongming Liang , Zhanyu Ma

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

计算机视觉与模式识别 · 计算机科学 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…

定量方法 · 定量生物学 2025-10-08 Anni Tziakouri , Filippo Menolascina

Existing Large Reasoning Models (LRMs) have shown the potential of reinforcement learning (RL) to enhance the complex reasoning capabilities of Large Language Models~(LLMs). While they achieve remarkable performance on challenging tasks…

人工智能 · 计算机科学 2025-03-19 Huatong Song , Jinhao Jiang , Yingqian Min , Jie Chen , Zhipeng Chen , Wayne Xin Zhao , Lei Fang , Ji-Rong Wen

Large Language Models (LLMs) excel at reasoning and generation but are inherently limited by static pretraining data, resulting in factual inaccuracies and weak adaptability to new information. Retrieval-Augmented Generation (RAG) addresses…

计算与语言 · 计算机科学 2025-11-03 Qi Luo , Xiaonan Li , Yuxin Wang , Tingshuo Fan , Yuan Li , Xinchi Chen , Xipeng Qiu

Recent advances in vision-language models (VLMs) have improved Chest X-ray (CXR) interpretation in multiple aspects. However, many medical VLMs rely solely on supervised fine-tuning (SFT), which optimizes next-token prediction without…