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Class-incremental learning (CIL) in medical image-guided diagnosis requires retaining prior diagnostic knowledge while adapting to newly emerging disease categories, which is critical for scalable clinical deployment. This problem is…

计算机视觉与模式识别 · 计算机科学 2026-03-26 Xinyao Wu , Zhe Xu , Cheng Chen , Jiawei Ma , Yefeng Zheng , Raymond Kai-yu Tong

This paper studies the problem of class-incremental learning (CIL), a core setting within continual learning where a model learns a sequence of tasks, each containing a distinct set of classes. Traditional CIL methods, which do not leverage…

机器学习 · 计算机科学 2025-11-19 Saleh Momeni , Changnan Xiao , Bing Liu

The survival analysis on histological whole-slide images (WSIs) is one of the most important means to estimate patient prognosis. Although many weakly-supervised deep learning models have been developed for gigapixel WSIs, their potential…

图像与视频处理 · 电气工程与系统科学 2023-11-06 Pei Liu , Luping Ji , Feng Ye , Bo Fu

Instance-incremental learning (IIL) focuses on learning continually with data of the same classes. Compared to class-incremental learning (CIL), the IIL is seldom explored because IIL suffers less from catastrophic forgetting (CF). However,…

机器学习 · 计算机科学 2024-06-06 Qiang Nie , Weifu Fu , Yuhuan Lin , Jialin Li , Yifeng Zhou , Yong Liu , Lei Zhu , Chengjie Wang

Class Incremental Learning (CIL) is challenging due to catastrophic forgetting. On top of that, Exemplar-free Class Incremental Learning is even more challenging due to forbidden access to previous task data. Recent exemplar-free CIL…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Zichong Meng , Jie Zhang , Changdi Yang , Zheng Zhan , Pu Zhao , Yanzhi Wang

Multiple Instance Learning (MIL) has become the predominant approach for classification tasks on gigapixel histopathology whole slide images (WSIs). Within the MIL framework, single WSIs (bags) are decomposed into patches (instances), with…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Daniel Sens , Ario Sadafi , Francesco Paolo Casale , Nassir Navab , Carsten Marr

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

图像与视频处理 · 电气工程与系统科学 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

In Continual learning (CL) balancing effective adaptation while combating catastrophic forgetting is a central challenge. Many of the recent best-performing methods utilize various forms of prior task data, e.g. a replay buffer, to tackle…

机器学习 · 计算机科学 2023-06-07 Nader Asadi , MohammadReza Davari , Sudhir Mudur , Rahaf Aljundi , Eugene Belilovsky

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

计算机视觉与模式识别 · 计算机科学 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

图像与视频处理 · 电气工程与系统科学 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Jiaxiang Gou , Luping Ji , Pei Liu , Mao Ye

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

计算机视觉与模式识别 · 计算机科学 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

Sebocytes are lipid-secreting cells whose differentiation is marked by the accumulation of intracellular lipid droplets, making their quantification a key readout in sebocyte biology. Manual counting is labor-intensive and subjective,…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Maryam Adelipour , Gustavo Carneiro , Jeongkwon Kim

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

计算机视觉与模式识别 · 计算机科学 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

Deep neural networks (DNNs) often suffer from "catastrophic forgetting" during incremental learning (IL) --- an abrupt degradation of performance on the original set of classes when the training objective is adapted to a newly added set of…

计算机视觉与模式识别 · 计算机科学 2020-01-17 Junting Zhang , Jie Zhang , Shalini Ghosh , Dawei Li , Serafettin Tasci , Larry Heck , Heming Zhang , C. -C. Jay Kuo

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

计算机视觉与模式识别 · 计算机科学 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…