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The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

计算与语言 · 计算机科学 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

计算与语言 · 计算机科学 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

计算与语言 · 计算机科学 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Large language models (LLMs) show potential as simulators of human behavior, offering a scalable way to study responses to interventions. However, because LLMs are trained largely on observational data, interventions in experiments with…

计算与语言 · 计算机科学 2026-05-21 Victoria Lin , Taedong Yun , Maja Matarić , John Canny , Arthur Gretton , Alexander D'Amour

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

计算与语言 · 计算机科学 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Large Language Models (LLMs) achieve strong performance through extended inference-time deliberation, yet how their reasoning failures arise remains poorly understood. By analyzing model-generated reasoning trajectories, we find that errors…

人工智能 · 计算机科学 2026-04-17 Wei Zhu , Jian Zhang , Lixing Yu , Kun Yue , Zhiwen Tang

Despite their remarkable abilities in various tasks, large language models (LLMs) still struggle with real-time information (e.g., new facts and terms) due to the knowledge cutoff in their development process. However, existing benchmarks…

计算与语言 · 计算机科学 2024-10-29 Hexuan Deng , Wenxiang Jiao , Xuebo Liu , Min Zhang , Zhaopeng Tu

The rapid advancement of Large Language Models (LLMs) has transformed knowledge-intensive has led to its widespread usage by knowledge workers to enhance their productivity. As these professionals handle sensitive information, and the…

人机交互 · 计算机科学 2025-07-28 Siying Hu , Piaohong Wang , Ka I Chan , Yaxing Yao , Zhicong Lu

Large Language Models (LLMs) have emerged as a promising cornerstone for the development of natural language processing (NLP) and artificial intelligence (AI). However, ensuring the robustness of LLMs remains a critical challenge. To…

计算与语言 · 计算机科学 2025-11-07 Pankaj Kumar , Subhankar Mishra

Large Language Models (LLMs) increasingly serve as knowledge interfaces, yet systematically assessing their reliability with conflicting information remains difficult. We propose an RDF-based framework to assess multilingual LLM quality,…

计算与语言 · 计算机科学 2025-05-01 Jonas Gwozdz , Andreas Both

Knowledge conflict arises from discrepancies between information in the context of a large language model (LLM) and the knowledge stored in its parameters. This can hurt performance when using standard decoding techniques, which tend to…

计算与语言 · 计算机科学 2025-04-30 Han Wang , Archiki Prasad , Elias Stengel-Eskin , Mohit Bansal

Large Language Models (LLMs) often produce explanations that do not faithfully reflect the factors driving their predictions. In healthcare settings, such unfaithfulness is especially problematic: explanations that omit salient clinical…

计算与语言 · 计算机科学 2025-11-04 Teague McMillan , Gabriele Dominici , Martin Gjoreski , Marc Langheinrich

The conformity bias exhibited by large language models (LLMs) can pose a significant challenge to decision-making in LLM-based multi-agent systems (LLM-MAS). While many prior studies have treated "conformity" simply as a matter of opinion…

人工智能 · 计算机科学 2026-04-22 Mikako Bito , Keita Nishimoto , Kimitaka Asatani , Ichiro Sakata

This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four…

计算与语言 · 计算机科学 2025-02-18 Shuqi Yang , Mingrui Jing , Shuai Wang , Jiaxin Kou , Manfei Shi , Weijie Xing , Yan Hu , Zheng Zhu

Clinical practice guidelines (CPGs) play a pivotal role in ensuring evidence-based decision-making and improving patient outcomes. While Large Language Models (LLMs) are increasingly deployed in healthcare scenarios, it is unclear to which…

计算与语言 · 计算机科学 2026-03-27 Andong Tan , Shuyu Dai , Jinglu Wang , Fengtao Zhou , Yan Lu , Xi Wang , Yingcong Chen , Can Yang , Shujie Liu , Hao Chen

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

计算与语言 · 计算机科学 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

计算与语言 · 计算机科学 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances…

计算与语言 · 计算机科学 2024-11-12 Iñigo Alonso , Maite Oronoz , Rodrigo Agerri

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

计算与语言 · 计算机科学 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes