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Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

计算与语言 · 计算机科学 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

计算与语言 · 计算机科学 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

计算与语言 · 计算机科学 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

计算与语言 · 计算机科学 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

Large language models (LLMs) have achieved remarkable success across a wide range of applications especially when augmented by external knowledge through retrieval-augmented generation (RAG). Despite their widespread adoption, recent…

计算与语言 · 计算机科学 2026-04-14 Tianzhe Zhao , Jiaoyan Chen , Shuxiu Zhang , Haiping Zhu , Qika Lin , Jun Liu

Clinical guidelines, typically structured as decision trees, are central to evidence-based medical practice and critical for ensuring safe and accurate diagnostic decision-making. However, it remains unclear whether Large Language Models…

计算与语言 · 计算机科学 2025-05-20 Xiaomin Li , Mingye Gao , Yuexing Hao , Taoran Li , Guangya Wan , Zihan Wang , Yijun Wang

Large language models (LLMs) have shown substantial progress in natural language understanding and generation, proving valuable especially in the medical field. Despite advancements, challenges persist due to the complexity and diversity…

计算与语言 · 计算机科学 2024-10-18 Yusheng Liao , Shuyang Jiang , Zhe Chen , Yanfeng Wang , Yu Wang

Large language models (LLMs) are emerging as valuable tools to support clinicians in routine decision-making. HIV management is a compelling use case due to its complexity, including diverse treatment options, comorbidities, and adherence…

计算与语言 · 计算机科学 2025-07-28 Gonzalo Cardenal-Antolin , Jacques Fellay , Bashkim Jaha , Roger Kouyos , Niko Beerenwinkel , Diane Duroux

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

计算机与社会 · 计算机科学 2026-03-03 Sanjay Basu

Large language models (LLMs) have shown remarkable promise but remain challenging to continually improve through traditional finetuning, particularly when integrating capabilities from other specialized LLMs. Popular methods like ensemble…

Large language models (LLMs) often need to balance their internal parametric knowledge with external information, such as user beliefs and content from retrieved documents, in real-world scenarios like RAG or chat-based systems. A model's…

计算与语言 · 计算机科学 2026-04-27 Shuowei Li , Haoxin Li , Wenda Chu , Yi Fang

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

计算与语言 · 计算机科学 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

In high-stakes information domains such as healthcare, where large language models (LLMs) can produce hallucinations or misinformation, retrieval-augmented generation (RAG) has been proposed as a mitigation strategy, grounding model outputs…

信息检索 · 计算机科学 2026-04-07 Saeedeh Javadi , Sara Mirabi , Manan Gangar , Bahadorreza Ofoghi

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

信息检索 · 计算机科学 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

计算与语言 · 计算机科学 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Multimodal large language models (MLLMs) have shown promising capabilities but struggle under distribution shifts, where evaluation data differ from instruction tuning distributions. Although previous works have provided empirical…

人工智能 · 计算机科学 2025-05-27 Changdae Oh , Zhen Fang , Shawn Im , Xuefeng Du , Yixuan Li

Recent advancements in large language models (LLMs) have shown their potential across both general and domain-specific tasks. However, there is a growing concern regarding their lack of sensitivity, factual incorrectness in responses,…

计算与语言 · 计算机科学 2025-12-01 Vivek Kumar , Pushpraj Singh Rajawat , Eirini Ntoutsi

Continual learning (CL) in large language models (LLMs) is an evolving domain that focuses on developing efficient and sustainable training strategies to adapt models to emerging knowledge and achieve robustness in dynamic environments. Our…

计算与语言 · 计算机科学 2025-02-13 Çağatay Yıldız , Nishaanth Kanna Ravichandran , Nitin Sharma , Matthias Bethge , Beyza Ermis

Large language models (LLMs) have been widely adopted in various downstream task domains. However, their abilities to directly recall and apply factual medical knowledge remains under-explored. Most existing medical QA benchmarks assess…

计算与语言 · 计算机科学 2025-08-20 Jiaxi Li , Yiwei Wang , Kai Zhang , Yujun Cai , Bryan Hooi , Nanyun Peng , Kai-Wei Chang , Jin Lu

Knowledge-intensive language understanding tasks require Language Models (LMs) to integrate relevant context, mitigating their inherent weaknesses, such as incomplete or outdated knowledge. However, conflicting knowledge can be present in…

计算与语言 · 计算机科学 2024-10-08 Sara Vera Marjanović , Haeun Yu , Pepa Atanasova , Maria Maistro , Christina Lioma , Isabelle Augenstein